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852395 MMS4

852395

MMS4

Mms4p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Mms4p

研究结论

Date Results Publications
2020-12-05 13:02:00 Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity. 33184279
2020-08-01 14:20:00 Study presents evidence that yeast Mus81-Mms4 endonuclease contributes to cell viability in the absence of functional telomerase. This involvement is not through recombination-mediated telomere lengthening as proposed in humans, but rather through an indirect role involving replication stress. 32469862
2019-03-02 12:37:00 These results strongly support the notion that Rad52 and Mus81-Mms4 collaborate and work jointly in processing of homologous recombination intermediates. 29738624
2018-05-19 10:23:00 Identification of new interacting partners and modulators of Mus81-Mms4 nuclease, RFC, and PCNA imply the cooperation of these factors in resolution of stalled replication forks and branched DNA structures emanating from the restarted replication forks under conditions of replication stress. 28969641
2017-07-08 12:53:00 The scaffold protein Rtt107, which binds the Mus81-Mms4 complex, interacts with Cdc7 and thereby targets Cdc7-Dbf4 and Cdc5 to the complex enabling full Mus81 activation. 28096179

名称对应

Type IDs
Synonymous SLX2, YBR100W
Gene
UniProtKB-ID: MMS4_YEAST
UniprotKB: P38257
UniParc: UPI000006AF56
EMBL: X78993, Z35968, AY692931, U14000, Z35967, BK006936
EnsemblGenome: YBR098W
KO: sce:YBR098W
Nucleutide sequences
EMBL-CDS: AAF06816.1, CAA85051.1, CAA55603.1, CAA85054.1, AAT92950.1, DAA07219.1
Gene_ORFName: YBR0826, YBR100W, YBR0829
EnsemblGenome_TRS: YBR098W_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR098W
RefSeq: NP_009656.2
Others
UniRef100: UniRef100_P38257
UniRef90: UniRef90_P38257
UniRef50: UniRef50_P38257

全选

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研究热度

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