Mlycd - malonyl-CoA decarboxylase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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85239 Mlycd

基因描述

Type	Description
Definition	malonyl-CoA decarboxylase

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Genomic organization and characterization of the promoter of teh malonyl-CoA decarboxylase gene	12151105
2010-01-21 00:00:00	substantial amounts of MCD protein and activity were found in the cytosol, mitochondria and peroxisomes, the latter with the highest specific activity	16298369
2010-01-21 00:00:00	differential regulation of malonyl CoA decarboxylase expression and activity in the mitochondria by AMP kinase may potentially regulate malonyl-CoA levels at sites nearby CPT-I on the mitochondria	15206948
2010-01-21 00:00:00	Increasing myocardial malonyl CoA levels decreases fatty acid oxidation & accelerates glucose oxidation in ex vivo rat hearts This switch in energy substrate preference improves cardiac function during & after ischemia.	15105298
2010-01-21 00:00:00	Mlycd regulation in rat in response to exercise	12065578

名称对应

Type	IDs
Synonymous	Mcd
Gene	UniProtKB-ID: DCMC_RAT UniprotKB: Q920F5 UniParc: UPI00000E7F76, UPI0000D7A48B EMBL: BC061845, AF304865, AJ007704 Ensembl: ENSRNOG00000014522 KO: rno:85239
Nucleutide sequences	EMBL-CDS: AAL09352.1, CAB46681.1, AAH61845.1 Ensembl_TRS: ENSRNOT00000019923
Protein sequencees	Ensembl_PRO: ENSRNOP00000019923 RefSeq: NP_445929.1
Others	UniRef100: UniRef100_Q920F5 UniRef90: UniRef90_Q920F5 UniRef50: UniRef50_Q920F5 UniGene: Rn.13468

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26767982	Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein. Am. J. Physiol. Gastrointest. Liver Physiol. Juliette Martin , Maria L Balmer , Saranya Rajendran , Olivier Maurhofer , Jean-FranÃ§ois Dufour , Marie V St-Pierre	2016-04-01	-
23791943	Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure D Sean Froese , Farhad Forouhar , Timothy H Tran , Melanie Vollmar , Yi Seul Kim , Scott Lew , Helen Neely , Jayaraman Seetharaman , Yang Shen , Rong Xiao , Thomas B Acton , John K Everett , Giuseppe Cannone , Sriharsha Puranik , Pavel Savitsky , Tobias Krojer , Ewa S Pilka , Wasim Kiyani , Wen Hwa Lee , Brian D Marsden , Frank von Delft , Charles K Allerston , Laura Spagnolo , Opher Gileadi , Gaetano T Montelione , Udo Oppermann , Wyatt W Yue , Liang Tong	2013-07-02	-
23746352	SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol. Cell GaÃ«lle Laurent , Natalie J German , Asish K Saha , Vincent C J de Boer , Michael Davies , Timothy R Koves , Noah Dephoure , Frank Fischer , Gina Boanca , Bhavapriya Vaitheesvaran , Scott B Lovitch , Arlene H Sharpe , Irwin J Kurland , Clemens Steegborn , Steven P Gygi , Deborah M Muoio , Neil B Ruderman , Marcia C Haigis	2013-06-06	Mlycd, Sirt4
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20178365	A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities. J Am Chem Soc Debdip Ghosh , Jeremy M Berg	2010-03-24	-
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1
18314420	Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. Diabetes Karim Bouzakri , Reginald Austin , Anna Rune , Michael E Lassman , Pablo M Garcia-Roves , Joel P Berger , Anna Krook , Alexander V Chibalin , Bei B Zhang , Juleen R Zierath	2008-06-01	MLYCD
17316539	Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. Anal. Biochem. Xiao Wang , William C Stanley , Cory J Darrow , Henri Brunengraber , Takhar Kasumov	2007-04-15	Mlycd
16298369	Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes. FEBS Lett. Erik Joly , Moise Bendayan , RaphaÃ«l Roduit , Asish K Saha , Neil B Ruderman , Marc Prentki	2005-12-05	Mlycd
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7

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