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852386 NHP6B

852386

NHP6B

high-mobility group nucleosome-binding protein

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition high-mobility group nucleosome-binding protein

研究结论

Date Results Publications
2020-07-11 10:28:00 he absence of chromatin regulators like Nhp6 A and B, interferes with a regulative circular mechanism where histone modification, transcription and metabolism influence each other and contribute to clarify the more general phenomenon in which gene regulation feeds metabolic alterations on epigenetic basis. 31676292
2017-11-04 11:33:00 Nhp6 proteins, the HMGB1 homologues, control histone gene expression by affecting nucleosome stability at regulative regions of the histone clusters. In addition, we observe that histone gene overexpression in the nhp6ab mutant is accompanied by downregulated translation, which in turn is responsible for the histone decrease phenotype. 28025045
2010-05-03 11:15:00 This review describes the genetic and biochemical experiments that indicate Nhp6 functions in promoting RNA pol III transcription, in formation of preinitiation complexes at promoters, and in facilitating the activity of chromatin modifying complexes. 20123079
2010-01-21 00:00:00 The incorporation of the histone variant H2A.Z, but not the HMG proteins Nhp6a/b, in promoter regions creates a specialized chromatin domain that is required for pre-initiation complex assembly at the GAL1 locus. 18331823
2010-01-21 00:00:00 Combining either a nhp6ab or a gcn5 mutation with mot1, ccr4, not4, or not5 mutations results in lethality. 16272410

名称对应

Type IDs
Synonymous YBR090C-A
Gene
UniProtKB-ID: NHP6B_YEAST
UniprotKB: P11633
UniParc: UPI0000130038
EMBL: AY558566, X78993, Z35959, X15318, Z35957, BK006936, EF123125
EnsemblGenome: YBR089C-A
KO: sce:YBR089C-A
Nucleutide sequences
EMBL-CDS: AAS56892.1, DAA07210.2, CAA85040.1, CAA33378.1, CAA85042.1, ABM97469.1
Gene_ORFName: YBR090BC
EnsemblGenome_TRS: YBR089C-A_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR089C-A
RefSeq: NP_009647.2
Others
UniRef100: UniRef100_P11633
UniRef90: UniRef90_P11633
UniRef50: UniRef50_P11633

全选

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