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852294 HHF1

852294

HHF1

histone H4

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition histone H4

研究结论

Date Results Publications
2018-01-13 14:14:00 The authors show that yeast chromatin assembly factor 1 binding to a histone H3-H4 dimer activates the Cac1 winged helix domain interaction with DNA. This drives the formation of a transient intermediate containing two chromatin assembly factor 1 complexes, each associated with one H3-H4 dimer. Here, the (H3-H4)2 tetramer is formed and deposited onto DNA. 28315523
2018-01-13 12:46:00 Here, the authors report that yeast chromatin assembly factor 1 (CAF1), a conserved histone chaperone complex that deposits H3-H4 during DNA replication, binds a single H3-H4 heterodimer in solution. 28315525
2018-01-13 10:28:00 Here the authors mapped the H4-tail binding pocket of ISWI. Surprisingly the binding site was adjacent to but not overlapping with the docking site of an auto-regulatory motif, AutoN, in the N-terminal region (NTR) of ISWI, indicating that AutoN does not act as a simple pseudosubstrate as suggested previously. 28109157
2017-09-09 11:49:00 The NuA4 core complex acetylates nucleosomal histone H4 through a double recognition mechanism. 27594449
2016-05-07 10:03:00 Here, we find that Sas2-dependent acetylated histone H4 K16Ac in bulk histones requires passage of the cells through the S-phase of the cell cycle, and the rate of increase in H4 K16Ac depends on both CAF-I and Asf1. 26260510

名称对应

Type IDs
Gene
UniProtKB-ID: H4_YEAST
UniprotKB: P02309
UniParc: UPI000004F8D3
EMBL: Z71306, BK006936, X00725, Z35878, BK006947, K03154, AY692960, X00724
EnsemblGenome: YBR009C, YNL030W
KO: sce:YNL030W, sce:YBR009C
Nucleutide sequences
EMBL-CDS: AAA34660.1, CAA25311.1, CAA84947.1, DAA07130.1, DAA10515.1, CAA95892.1, AAT92979.1, CAA25313.1
Gene_ORFName: N2752, YBR0122
EnsemblGenome_TRS: YBR009C_mRNA, YNL030W_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR009C, YNL030W
RefSeq: NP_009563.1
Others
UniRef100: UniRef100_P02309
UniRef90: UniRef90_P02309
UniRef50: UniRef50_P02309

全选

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