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852283 HTA2

852283

HTA2

histone H2A

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition histone H2A

研究结论

Date Results Publications
2020-05-30 13:04:00 H2A.1 promotes high-fidelity homologous recombination, sister chromatid recombination (SCR), and break-induced replication whereas H2A.2 does not share these functions. Both decreased SCR and the increase in CAG expansions were due to the unique Thr126 residue in H2A.1 and hta1Delta or hta1-T126A mutants were epistatic to deletion of the Poldelta subunit Pol32, suggesting a role for H2A.1 in D-loop extension. 31804179
2015-08-22 10:30:00 The data identifies novel roles of the histone H2A N-tail in (i) regulating the expression of a critical BER enzyme (Mag1), (ii) supporting efficient DNA damage signaling and (iii) facilitating postreplication repair. 25897129
2010-01-21 00:00:00 H2A phosphorylation promotes two independent events, rapid Rad9 recruitment to DSBs and subsequent remodeling by NuA4, SWR, and INO80. 16940359

名称对应

Type IDs
Synonymous H2A2
Gene
UniProtKB-ID: H2A2_YEAST
UniprotKB: P04912
UniParc: UPI0000036CFA
EMBL: BK006936, Z26494, Z35764, V01305, AY693115
EnsemblGenome: YBL003C
KO: sce:YBL003C
Nucleutide sequences
EMBL-CDS: CAA81267.1, CAA84818.1, AAT93134.1, CAA24612.1, DAA07119.1
Gene_ORFName: YBL0103
EnsemblGenome_TRS: YBL003C_mRNA
Protein sequencees
EnsemblGenome_PRO: YBL003C
RefSeq: NP_009552.1
Others
UniRef100: UniRef100_P04912
UniRef90: UniRef90_P04911
UniRef50: UniRef50_P16104

全选

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研究热度

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