| Type | Description |
|---|---|
| Definition | Hir1p |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 11:23:00 | our study identified a novel mechanism by which H3K4me3 antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and extend chronological life span. | 30759223 |
| 2012-05-05 10:50:00 | inactivation of the negative regulatory system by deletion of the HIR1 gene relieved the dependence of HTA1-HTB1 transcription on the mitotic Clb1/Cb2 cyclins | 21978826 |
| 2012-03-10 10:25:00 | nucleosome shielding is the primary means to maintain promoter fidelity, and histone replacement is most efficiently mediated in yeast cells by a HIR/Asf1/H3-H4/Rtt106 pathway. | 22128187 |
| 2010-01-21 00:00:00 | Asf1 and HIR are important for histone deposition but each has a different effect on histone exchange | 17914459 |
| 2010-01-21 00:00:00 | overexpression of HIR1 in the Kllsm4Delta1 mutant prevented rapid cell death during aging, reduced nuclei fragmentation & increased resistance to H2O2; expression of histone genes is lowered in the mutant indicating a relationship between HIR1 & apoptosis | 16169287 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HIR1_YEAST
UniprotKB:
P32479
UniParc:
UPI0001F7BD23
EMBL:
BK006936,
Z35769,
L03838,
S47695
EnsemblGenome:
YBL008W
KO:
sce:YBL008W
|
| Nucleutide sequences |
EMBL-CDS:
CAA84827.1,
DAA07112.2,
AAB23989.1
Gene_ORFName:
YBL0318
EnsemblGenome_TRS:
YBL008W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBL008W
RefSeq:
NP_009545.2
|
| Others |
UniRef100:
UniRef100_P32479
UniRef90:
UniRef90_P32479
UniRef50:
UniRef50_P32479
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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