| Type | Description |
|---|---|
| Definition | growth arrest specific 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:55:00 | Reported here is the solution NMR structure of Gas7 SH3 domain which displays a typical SH3 beta-barrel fold comprising five beta-strands and one 310-helix. Structural and sequence comparison showed that Gas7-SH3 shares high similarity with Abl SH3 domain, which binds to a high-affinity proline-rich peptide P41 in a canonical SH3-ligand binding mode through two hydrophobic pockets and a specificity site in the RT-loop. | 31296381 |
| 2020-04-04 10:44:00 | Single nucleotide polymorphism in GAS7 gene is associated as a protective factor for primary open-Angle Glaucoma. | 31269845 |
| 2019-03-02 11:07:00 | A novel regulatory mechanism of p53 in early onset breast cancer progression through GAS7-CYFIP1-mediated signaling pathways. | 29706651 |
| 2018-03-24 11:51:00 | Polymorphism rs11656696 is not associated with primary open angle glaucoma (POAG) nor any of its endophenotypic traits such as intraocular pressure and cup/disk ratio and is thus not a risk factor for POAG in this Saudi cohort | 29022762 |
| 2018-02-24 11:45:00 | Collectively, our findings provide a novel basis for using miR-181a/GAS7-based therapeutic strategies to reverse gefitinib resistance in NSCLC. | 29269300 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GAS7_HUMAN
UniprotKB:
O60861
UniParc:
UPI000012B0E5,
UPI00001B4B17,
UPI000002AA32,
UPI000023C3D6
EMBL:
BC006454,
AC107938,
AK292987,
AF231998,
CH471108,
AK315162,
AJ224876,
AC000003,
AB007854,
BT006891,
AY327406,
AC005747,
AC026591,
AC083783,
BC001152
Ensembl:
ENSG00000007237
KO:
hsa:8522
|
| Nucleutide sequences |
EMBL-CDS:
BAG37606.1,
BAA23690.2,
CAA12177.1,
EAW90011.1,
AAG26332.2,
BAF85676.1,
AAH01152.1,
AAP35537.1,
EAW90012.1,
AAH06454.2,
AAP92798.1,
EAW90013.1
Ensembl_TRS:
ENST00000542249,
ENST00000585266,
ENST00000579158,
ENST00000323816,
ENST00000580865,
ENST00000432992,
ENST00000437099
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407552,
ENSP00000464240,
ENSP00000463873,
ENSP00000410108,
ENSP00000322608,
ENSP00000443265,
ENSP00000463527
RefSeq:
NP_958836.1,
XP_005256889.1,
XP_016880729.1,
XP_016880730.1,
XP_016880731.1,
XP_016880728.1,
XP_005256890.1,
XP_005256892.1,
XP_011522346.1,
NP_958839.1,
XP_005256891.1,
NP_001124303.1,
NP_003635.2,
XP_005256888.1
|
| Others |
UniRef100:
UniRef100_O60861
UniRef90:
UniRef90_O60861
UniRef50:
UniRef50_O60861
UniGene:
Hs.462214
CCDS:
CCDS58518.1,
CCDS11152.1,
CCDS42263.1,
CCDS45611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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