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852150 PAD1

852150

PAD1

phenylacrylic acid decarboxylase PAD1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition phenylacrylic acid decarboxylase PAD1

研究结论

Date Results Publications
2018-06-09 11:17:00 Ferulic acid decarboxylase catalyzes the decarboxylation of phenylacrylic acid using a newly identified cofactor, prenylated flavin mononucleotide (prFMN). The proposed mechanism involves the formation of a putative pentacyclic intermediate formed by a 1,3 dipolar cyclo-addition of prFMN with the alpha-beta double bond of the substrate, which serves to activate the substrate toward decarboxylation. 28753302
2018-06-02 10:26:00 The kinetics and substrate requirements of prenyl-flavin synthase were determined. Dimethylallyl pyrophosphate is the prenyl donor. The kinetics of the reaction are extremely slow: kcat = 12.2 +/- 0.2 h(-1), and KM for dimethylallyl pyrophosphate = 9.8 +/- 0.7 muM. The reaction of FMN was described well by first-order kinetics with a kapp of 17.4 +/- 1.1 h(-1). scPFS. 29232110
2016-05-07 11:56:00 synthesizes a cofactor required by FDC (ferulic acid decarboxylase) for decarboxylase activity. 25647642
2012-06-16 12:31:00 POF1 is an ATPase that is likely involved in the protein degradation pathway. 22204397
2010-07-26 12:13:00 examination of the contribution of the gene to the decarboxylation of phenylacrylic acid using gene disruptants and the corresponding transformants in which the disrupted genes were recovered. 20471595

名称对应

Type IDs
Synonymous POF1
Gene
UniProtKB-ID: PAD1_YEAST
UniprotKB: P33751
UniParc: UPI00001311E7
EMBL: BK006938, U43834, L09263
EnsemblGenome: YDR538W
KO: sce:YDR538W
Nucleutide sequences
EMBL-CDS: AAA20484.1, DAA12367.1, AAB64980.1
EnsemblGenome_TRS: YDR538W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR538W
RefSeq: NP_010827.3
Others
UniRef100: UniRef100_P33751
UniRef90: UniRef90_P33751
UniRef50: UniRef50_P33751

全选

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