CAB1 - pantothenate kinase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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852144 CAB1

基因描述

Type	Description
Definition	pantothenate kinase

研究结论

Date	Results	Publications
2020-05-09 10:03:00	Here, we show that the pantothenate kinase Cab1p, which catalyzes the first step in the metabolism of pantothenic acid for CoA biosynthesis in budding yeast (Saccharomyces cerevisiae), significantly regulates the levels of sterol intermediates and the activities of ergosterol biosynthesis-targeting antifungals.	31409644
2010-01-21 00:00:00	Complementation studies by bacterial and mammalian genes showed that YDR531W encodes a genuine pantothenate kinase (new gene designation: CAB1, "coenzyme A biosynthesis").	19266201

名称对应

Type	IDs
Gene	UniProtKB-ID: PANK_YEAST UniprotKB: Q04430 UniParc: UPI000006B72E EMBL: BK006938, U33057 EnsemblGenome: YDR531W KO: sce:YDR531W
Nucleutide sequences	EMBL-CDS: DAA12362.1, AAB64970.1 EnsemblGenome_TRS: YDR531W_mRNA
Protein sequencees	EnsemblGenome_PRO: YDR531W RefSeq: NP_010820.3
Others	UniRef100: UniRef100_Q04430 UniRef90: UniRef90_Q04430 UniRef50: UniRef50_Q04430

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
33115720	Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) Elsbeth Sanders , Phoebe A Nguyen , Cody M Rogers , Matthew L Bochman	2020-12-03	-
31409644	The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors. J Biol Chem Joy E Chiu , Jose Thekkiniath , Sameet Mehta , Christoph MÃ¼ller , Franz Bracher , Choukri Ben Mamoun	2019-10-04	-
29702647	Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet Harley O'Connor Mount , Nicole M Revie , Robert T Todd , Kaitlin Anstett , Cathy Collins , Michael Costanzo , Charles Boone , Nicole Robbins , Anna Selmecki , Leah E Cowen	2018-04-01	-
29158339	Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese	2018-01-04	-
27708008	A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone	2016-09-23	-
26668354	Target selection by natural and redesigned PUF proteins. Proc. Natl. Acad. Sci. U.S.A. Douglas F Porter , Yvonne Y Koh , Brett VanVeller , Ronald T Raines , Marvin Wickens	2016-12-29	-
23390603	Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) Derek M van Pel , Peter C Stirling , Sean W Minaker , Payal Sipahimalani , Philip Hieter	2013-02-01	-
23332755	The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell Felix Willmund , Marta del Alamo , Sebastian Pechmann , Taotao Chen , VÃ©ronique AlbanÃ¨se , Eric B Dammer , Junmin Peng , Judith Frydman	2013-01-17	VAC17, MIC10, PRD1, KAR4, PBN1, APA1, POF1, MGR1, GLK1, SRO9, GFD2, GRX1, LSB5, RNQ1, HBN1, DCC1, GBP2, ILV6, STP22, CDC10, YCP4, CIT2, RVS161, PGK1, RHB1, RIM1, SYP1, RPS14A, RRP43, YCR043C, YCR051W, THR4, CTR86, PWP2, YIH1, TAH1, HCM1, RSA4, SOL2, FUB1, PAT1, AHC2, TRX3, TUP1, CSM1, YCR090C, MSH3, YCR102C, SNZ3, SWP82, RGD2, SEC53, OTU1, ACT1, YPT1, TUB2, MOB2, RPL22B, HAC1, CAF16, FRS2, GAT1, LPD1, BLM10, SEC4, VTC2, SPB4, RPN11, YFR006W, YFH7, IOC3, ATG18, LSB3, HIS2, CDC14, RPL2A, DUG1, BNA6, RMD8, YMR31, PRE4, RET2, RPN12, HXK1, IRC7, GRC3, RIX7, YLL032C, FRA1, ISA1, HSP104, SSA2, HIF1, DPS1, LMO1, ORC3, RTT109, MHT1, YLL058W
22282571	Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res. Sara Sharifpoor , Dewald van Dyk , Michael Costanzo , Anastasia Baryshnikova , Helena Friesen , Alison C Douglas , Ji-Young Youn , Benjamin VanderSluis , Chad L Myers , BalÃ¡zs Papp , Charles Boone , Brenda J Andrews	2012-04-01	SUS1, VMA9, YCL075W, YCL074W, VAC17, MRC1, PEX34, KAR4, PBN1, LRE1, SPS22, MGR1, YCL042W, GLK1, GID7, ATG22, SRO9, STE50, RRP7, BIK1, FUS1, FRM2, AGP1, DCC1, BUD3, SGF29, ILV6, YCL002C, RER1, CDC10, YCR007C, SAT4, RVS161, ADP1, YCR016W, CWH43, MAK32, PET18, SLM5, RIM1, SYP1, BPH1, SNT1, ELO2, PER1, YCR051W, THR4, TAH1, YCR061W, BUD31, RAD18, SED4, ATG15, IMG2, RSA4, SOL2, ERS1, PAT1, TRX3, CSM1, ABP1, YCR090C, KIN82, YCR102C, PAU3, YFL068W, AGP3, YFL054C, ZNF1, SWP82, SEC53, YFL040W, ACT1, YPT1, RPO41, RIM15, BST1, BUD27, FRS2, MDJ1, HSP12, IES1, BLM10, VTC2, DEG1, RPN11, FAR7, GCN20, UBP6, DCV1, CMK1, GSY1, PES4, PTR3, MET10, RRT5, RPL29, RSC8, SAP155
21987634	A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J. Cell Biol. Suzanne Hoppins , Sean R Collins , Ann Cassidy-Stone , Eric Hummel , Rachel M Devay , Laura L Lackner , Benedikt Westermann , Maya Schuldiner , Jonathan S Weissman , Jodi Nunnari	2011-10-17	CHA1, MRC1, MIC10, PBN1, EMC1, MGR1, PDI1, ATG22, STE50, AGP1, SGF29, ILV6, PGS1, RER1, CIT2, ADP1, POL4, CWH43, FEN2, SYP1, BPH1, ELO2, ARE1, THR4, SED4, ATG15, PAT1, TRX3, ABP1, AGP3, SWP82, FMP32, OTU1, RPO41, RIM15, HAC1, AGX1, BST1, LPD1, MDJ1, SEC4, DEG1, FAR7, UBP6, MIC19, YFR018C, FAB1, ATG18, QCR6, PHO4, ERJ5, DUG1, YFR045W, PRE4, RET2, RPN12, VPS13, UBI4, POM33, SPA2, EMC6, PUF3, MMM1, GTT2, YCT1, AQY2, ATG10, SDH2, DNM1, CMS1, IZH3, RIC1, PDC1, YLR050C, SPT8, ERG3, SHM2, REX2, PER33, MEF1, BOS1, GAL2, RAX2, SMC4, CSF1, GAA1, ALT1, XDJ1, GEP5, NYV1, APC9, CDC45, LCL2, CCW12, MSL5, YPS1, ZRT2, CKI1, PUT1

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