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8521 GCM1

8521

GCM1

glial cells missing transcription factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glial cells missing transcription factor 1

研究结论

Date Results Publications
2018-12-22 10:11:00 our studies demonstrate that DLX3 physically interacts with GCM1 and inhibits its transactivation activity, suggesting that DLX3 and GCM1 may form a complex to functionally regulate placental cell function through modulation of target gene expression. 28515447
2017-11-25 15:58:00 results suggest that p45 NF-E2 negatively regulates differentiation and apoptosis activation of human syncytiotrophoblast by modulating GCM1 acetylation and sumoylation. 28383551
2017-09-23 10:25:00 Identify a novel cis-acting sequence (-369 to -320) at the placental growth factor promoter, which was critical for mediating the basal and DLX3/GCM1-dependent PGF promoter activities. 27996093
2017-01-14 11:57:00 Twist1 may promote trophoblast syncytialization by regulating the expression of GCM1. 26992674
2016-12-31 11:49:00 GATA3 knockdown elevated HtrA4 expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion. 26899996

名称对应

Type IDs
Synonymous GCMA, hGCMa
Gene
UniProtKB-ID: GCM1_HUMAN
UniprotKB: Q9NP62
UniParc: UPI0000073F99
EMBL: AB041716, AB026493, AB041714, D88613, AL512347, AB047819, BC096288
Ensembl: ENSG00000137270
KO: hsa:8521
Nucleutide sequences
EMBL-CDS: BAA13651.1, BAB18039.1, BAA77250.2, BAA94757.1, AAH96288.1, BAA94758.1
Ensembl_TRS: ENST00000259803
Protein sequencees
Ensembl_PRO: ENSP00000259803
RefSeq: XP_016866879.1, NP_003634.2
Others
UniRef100: UniRef100_Q9NP62
UniRef90: UniRef90_Q9NP62
UniRef50: UniRef50_Q9NP62
UniGene: Hs.28346
CCDS: CCDS4950.1

全选

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