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852088 SNF1

852088

SNF1

AMP-activated serine/threonine-protein kinase catalytic subunit SNF1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition AMP-activated serine/threonine-protein kinase catalytic subunit SNF1

研究结论

Date Results Publications
2020-12-12 13:29:00 Snf1 AMPK positively regulates ER-phagy via expression control of Atg39 autophagy receptor in yeast ER stress response. 32986716
2020-09-12 16:03:00 Spontaneous mutations that confer resistance to 2-deoxyglucose act through Hxk2 and Snf1 pathways to regulate gene expression and HXT endocytosis. 32673313
2020-07-04 12:33:00 Downregulation of Snf1p suppressed Deltasit4 mutant phenotypes, including mitochondrial derepression, resistance to oxidative stress and increased lifespan. Overall, this indicates a more prominent role of Snf1p downstream the Sit4p signalling pathway than previously suspected. 31991152
2020-06-27 10:56:00 AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 (SNF1) deletion in Saccharomyces cerevisiae cells grown at 1% glucose, decreased glycolytic flux, increased NAD(P)H concentration, enhanced HXK2 gene transcription, and decreased mitochondrial respiration. SNF1 is important to respond to glucose concentration variation and is involved in the switch between mitochondrial respiration and fermentation. 31074533
2019-10-26 12:18:00 Study reports a novel role of Saccharomyces cerevisiae Snf1/AMPK in the progression through mitosis in glucose-repressing condition and shows that active Snf1 is localized to the bud neck from bud emergence to cytokinesis in a septin-dependent manner. In addition, loss of Snf1 induces a delay of the metaphase to anaphase transition that is due to a defect in the correct alignment of the mitotic spindle. 29643469

名称对应

Type IDs
Synonymous CAT1, CCR1, GLC2, HAF3, PAS14
Gene
UniProtKB-ID: SNF1_YEAST
UniprotKB: P06782
UniParc: UPI0000052F22
EMBL: M13971, U33050, BK006938
EnsemblGenome: YDR477W
KO: sce:YDR477W
Nucleutide sequences
EMBL-CDS: DAA12310.1, AAB64904.1, AAA35058.1
Gene_ORFName: D8035.20
EnsemblGenome_TRS: YDR477W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR477W
RefSeq: NP_010765.3
Others
UniRef100: UniRef100_P06782
UniRef90: UniRef90_P06782
UniRef50: UniRef50_P06782

全选

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