| Type | Description |
|---|---|
| Definition | E3 ubiquitin-protein ligase TOM1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-06 10:21:00 | Coimmunoprecipitation analysis confirmed that Tom1 and Spo12 interact. Overexpression of Spo12 is cytotoxic in the absence of Tom1. Notably, Spo12 is degraded in S phase even in the absence of Tom1 and Cdh1, suggesting that an additional E3 ligase(s) also mediates Spo12 degradation | 29683484 |
| 2017-10-28 11:45:00 | Together, these data point to an important role for Tom1, Ubc4 and Ubc5 in normal physiology and prompt the authors to refer to this pathway as ERISQ, for excess ribosomal protein quality control. | 27552055 |
| 2013-03-30 11:27:00 | Tom1 and the Dia2 control Cdc6 degradation in G1 phase. | 23129771 |
| 2010-01-21 00:00:00 | Data demonstrated that excess histones associate with Rad53, and also identified Ubc4 and Ubc5, as well as Tom1 as enzymes involved in the ubiquitylation of excess histones. | 19578373 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TOM1_YEAST
UniprotKB:
Q03280
UniParc:
UPI000006BC10
EMBL:
D63905,
BK006938,
U33050
EnsemblGenome:
YDR457W
KO:
sce:YDR457W
|
| Nucleutide sequences |
EMBL-CDS:
BAA21482.1,
AAB64910.1,
DAA12291.1
Gene_ORFName:
D8035.1
EnsemblGenome_TRS:
YDR457W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR457W
RefSeq:
NP_010745.3
|
| Others |
UniRef100:
UniRef100_Q03280
UniRef90:
UniRef90_Q03280
UniRef50:
UniRef50_Q03280
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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