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852066 NHX1

852066

NHX1

bifunctional K:H/Na:H antiporter NHX1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition bifunctional K:H/Na:H antiporter NHX1

研究结论

Date Results Publications
2012-05-12 11:11:00 Data suggest that Nhx1p plays an important role in regulation of the luminal pH of various intracellular organelles, and that this regulation is critical for the protein recycling pathway as well as the endocytic pathway. 22210050
2012-02-25 10:39:00 Nhx1 is not required for cargo sorting or multivesicular body formation and shows synthetic phenotypes with select endosomal sorting complex required for transport mutants 21998311
2011-12-17 11:39:00 Nhx1p contributes to MVB formation by the recruitment of Vps27p to the endosomal membrane, possibly through Nhx1p antiporter activity. 21896492
2011-02-26 10:24:00 The authors conclude that Arl1p, Kha1p and Nhx1p collaborate in survival strategies at nonoptimal pH, temperatures and cation concentrations, but work independent of each other. 20659170
2011-01-01 11:34:00 Gene knockout of NHX1 increases sensitivity to hygromycin and acidic pH in yeast cells. 20858221

名称对应

Type IDs
Synonymous NHA2, VPL27, VPS44
Gene
UniProtKB-ID: NHX1_YEAST
UniprotKB: Q04121
UniParc: UPI000012FD25
EMBL: BK006938, U33007
EnsemblGenome: YDR456W
KO: sce:YDR456W
Nucleutide sequences
EMBL-CDS: AAB64861.1, DAA12290.1
Gene_ORFName: D9461.40
EnsemblGenome_TRS: YDR456W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR456W
RefSeq: NP_010744.3
Others
UniRef100: UniRef100_Q04121
UniRef90: UniRef90_Q04121
UniRef50: UniRef50_Q04121

全选

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