| Type | Description |
|---|---|
| Definition | mRNA-binding protein NPL3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | The SR-protein Npl3 is an essential component of the meiotic splicing regulatory network in Saccharomyces cerevisiae. | 33577675 |
| 2019-04-06 10:55:00 | This study investigated the enzyme-substrate interaction between Hmt1p and nucleolar protein Npl3p, using chemical cross linking/mass spectrometry. This method can capture transient interprotein interactions that occur during the process of methylation, involving a disordered region in Npl3p with tandem SRGG repeats, and we confirm that Hmt1p and Npl3p exist as homomultimers. | 30004689 |
| 2017-12-02 11:18:00 | Npl3 participates in DNA double-strand break resection by promoting the proper biogenesis of EXO1 mRNA. | 28472517 |
| 2017-08-19 11:52:00 | a model in which Hmt1, via arginine methylation of Npl3, facilitates U1 snRNP engagement with the pre-mRNA to promote usage of non-consensus splice sites by the splicing machinery. | 28392442 |
| 2016-07-16 11:28:00 | Npl3 binds diverse sites on large numbers of transcripts, and the loss of Npl3 results in transcriptional readthrough on many genes. | 26694144 |
| Type | IDs |
|---|---|
| Synonymous | MTR13, MTS1, NAB1, NOP3 |
| Gene |
UniProtKB-ID:
NOP3_YEAST
UniprotKB:
Q01560
UniParc:
UPI00000530EC
EMBL:
U33007,
X66019,
X70951,
BK006938,
M86731
EnsemblGenome:
YDR432W
KO:
sce:YDR432W
|
| Nucleutide sequences |
EMBL-CDS:
CAA46817.1,
AAB64865.1,
CAA50291.1,
DAA12270.1,
AAA34818.1
Gene_ORFName:
D9461.19
EnsemblGenome_TRS:
YDR432W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR432W
RefSeq:
NP_010720.3
|
| Others |
UniRef100:
UniRef100_Q01560
UniRef90:
UniRef90_Q01560
UniRef50:
UniRef50_Q01560
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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