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852028 RAD30

852028

RAD30

DNA-directed DNA polymerase eta

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DNA-directed DNA polymerase eta

研究结论

Date Results Publications
2021-04-17 13:37:00 The interaction between ubiquitin and yeast polymerase eta C terminus does not require the UBZ domain. 32239506
2020-10-24 14:10:00 Bypass of DNA interstrand crosslinks by a Rev1-DNA polymerase zeta complex. 32633759
2019-11-30 12:08:00 Here we show that the translesion synthesis DNA polymerase eta (Pol eta) plays a role in DNA replication under low deoxyribonucleotides condition triggered by hydroxyurea. In particular, the catalytic reaction performed by Pol eta is detrimental for RNase H deficient cells, causing DNA damage checkpoint activation and G2/M arrest 30847483
2019-11-16 12:07:00 Lsm12 is a novel regulator mediating Poleta deubiquitination that regulates its recruitment in response to DNA damage induced by oxidative stress. 30366994
2019-10-19 12:26:00 these findings provide insight into the physiological role of DNA synthesis by pol eta and have implications for our understanding of how our genome is replicated to avoid mutagenesis, genome instability and cancer 30597049

名称对应

Type IDs
Synonymous DBH1
Gene
UniProtKB-ID: POLH_YEAST
UniprotKB: Q04049
UniParc: UPI000006B8F4
EMBL: BK006938, U33007
EnsemblGenome: YDR419W
KO: sce:YDR419W
Nucleutide sequences
EMBL-CDS: AAB64856.1, DAA12259.1
EnsemblGenome_TRS: YDR419W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR419W
RefSeq: NP_010707.3
Others
UniRef100: UniRef100_Q04049
UniRef90: UniRef90_Q04049
UniRef50: UniRef50_Q04049

全选

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研究热度

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