| Type | Description |
|---|---|
| Definition | Mus81p |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity. | 33184279 |
| 2020-08-01 14:20:00 | Study presents evidence that yeast Mus81-Mms4 endonuclease contributes to cell viability in the absence of functional telomerase. This involvement is not through recombination-mediated telomere lengthening as proposed in humans, but rather through an indirect role involving replication stress. These and other results suggest that Mus81 localization to the telomere may be a promising indicator for telomere dysfunction. | 32469862 |
| 2019-03-02 12:37:00 | These results strongly support the notion that Rad52 and Mus81-Mms4 collaborate and work jointly in processing of homologous recombination intermediates. | 29738624 |
| 2018-05-19 10:23:00 | Identification of new interacting partners and modulators of Mus81-Mms4 nuclease, RFC, and PCNA imply the cooperation of these factors in resolution of stalled replication forks and branched DNA structures emanating from the restarted replication forks under conditions of replication stress. | 28969641 |
| 2018-04-28 11:18:00 | The data suggest that subnuclear relocalization is relevant for the function of Mus81-Mms4 complex in response to DNA damage and, probably, of the endonucleases that colocalize with it. | 28813668 |
| Type | IDs |
|---|---|
| Synonymous | SLX3 |
| Gene |
UniProtKB-ID:
MUS81_YEAST
UniprotKB:
Q04149
UniParc:
UPI000006A8D4
EMBL:
BK006938,
U32274
EnsemblGenome:
YDR386W
KO:
sce:YDR386W
|
| Nucleutide sequences |
EMBL-CDS:
DAA12230.1,
AAB64828.1
Gene_ORFName:
D9509.6
EnsemblGenome_TRS:
YDR386W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR386W
RefSeq:
NP_010674.3
|
| Others |
UniRef100:
UniRef100_Q04149
UniRef90:
UniRef90_Q04149
UniRef50:
UniRef50_Q04149
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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