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851993 EFT2

851993

EFT2

elongation factor 2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition elongation factor 2

研究结论

Date Results Publications
2019-07-20 12:59:00 Chaperoning of eEF2 by Cns1 is essential for yeast viability and requires a defined subset of the Hsp90 machinery as well as the identified eEF2 recruiting factor Hgh1. 30876805
2019-07-20 12:59:00 Hgh1 binding recruits TRiC to the C-terminal eEF2 module and prevents unproductive interactions of domain III, allowing efficient folding of the N-terminal GTPase module. eEF2 folding is completed upon dissociation of TRiC and Hgh1. 30876804
2019-03-30 12:19:00 The histamine to diphthamide EFT2 substitution is important for translational accuracy and competitive cell growth in yeast. 30335802
2015-01-03 11:36:00 Deletion of EFM2 or EFM3 increased sensitivity to translation inhibitors, indicating changes in the ability for EF2 to interact and communicate with ribosomal components. 25231983
2010-01-21 00:00:00 findings show that the diphthamide-containing loop plays an important role in the ADP-ribosylation of eEF2 catalysed by toxin and also for modification of His699 by the endogenous diphthamide modification machinery 18373493

名称对应

Type IDs
Gene
UniProtKB-ID: EF2_YEAST
UniprotKB: P32324
UniParc: UPI00000534E7
EMBL: X90518, X94335, M59369, Z75041, BK006938, BK006948, M59370, U32274, U28373, AY497635
EnsemblGenome: YDR385W, YOR133W
KO: sce:YOR133W, sce:YDR385W
Nucleutide sequences
EMBL-CDS: CAA62116.1, CAA99332.1, DAA10907.1, AAA51398.1, AAA21646.1, CAA64052.1, DAA12229.1, AAB64821.1, AAB64827.1, AAT12549.1
Gene_ORFName: O3317, YOR3317W
EnsemblGenome_TRS: YDR385W_mRNA, YOR133W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR385W, YOR133W
RefSeq: NP_010673.1
Others
UniRef100: UniRef100_P32324
UniRef90: UniRef90_P32324
UniRef50: UniRef50_P32324

全选

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