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851988 YRA1

851988

YRA1

RNA-binding protein YRA1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition RNA-binding protein YRA1

研究结论

Date Results Publications
2019-12-21 10:53:00 the data provide evidence that Yra1 plays a crucial role in DSB repair via homologous recombination. While Yra1 sumoylation and/or ubiquitination are dispensable, the Yra1 C-box region is essential in this process. 30951522
2018-08-11 12:01:00 Yra1 binds RNA-DNA hybrids in vitro and, when artificially overexpressed, can be recruited to chromatin in an RNA-DNA hybrid-dependent manner, stabilizing R loops and converting them into replication obstacles in vivo 29954833
2018-02-10 11:31:00 Both THO and Yra1-C stimulated Sub2's intrinsic ATPase activity. The authors propose that THO surveys common landmarks in each nuclear mRNP to localize Sub2 for targeted loading of Yra1. 28059701
2016-08-27 10:52:00 YRA1 overexpression causes a cell senescence-like phenotype and telomere shortening 27035147
2016-08-20 11:43:00 These data show that Yra1 inhibits unwinding in a concentration-dependent manner by preventing the association of Dbp2 with single-stranded RNA. 26876600

名称对应

Type IDs
Synonymous SHE11
Gene
UniProtKB-ID: YRA1_YEAST
UniprotKB: Q12159
UniParc: UPI0000052E0B
EMBL: U28373, U32274, U72633, BK006938
EnsemblGenome: YDR381W
KO: sce:YDR381W
Nucleutide sequences
EMBL-CDS: DAA12224.1, AAB64817.1, AAC09951.1, AAB64823.1
Gene_ORFName: D9509.1, D9481.2
EnsemblGenome_TRS: YDR381W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR381W
RefSeq: NP_010669.1
Others
UniRef100: UniRef100_Q12159
UniRef90: UniRef90_Q12159
UniRef50: UniRef50_Q12159

全选

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研究热度

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