| Type | Description |
|---|---|
| Definition | bifunctional AAA family ATPase chaperone/translocase BCS1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:48:00 | This study presents the structure of Saccharomyces cerevisiae Bcs1, an AAA-ATPase of the inner mitochondrial membrane. Bcs1 facilitates the translocation of the Rieske protein, Rip1, which requires folding and incorporation of a 2Fe-2S cluster before translocation and subsequent integration into the bc1 complex. | 31988523 |
| 2018-02-10 11:12:00 | We found that the absence of non-essential translation factors Rrf1 or Mif3, which act at the recycling/initiation steps, also compensates for the respiratory deficiency of yeast bcs1 mutations | 28888990 |
| 2014-04-26 12:29:00 | The ATP dependency of the protein Bcs1 is not just a requirement for its chaperon activity but also a way to couple the rate of complex III biogenesis to the energy-transducing activity of mitochondria. | 24055101 |
| 2014-03-22 11:42:00 | The evolutionarily-conserved short alpha helix of Bcs1 in the intermembrane space is an essential element for the chaperone function. | 24361883 |
| 2011-12-31 10:39:00 | The oligomeric AAA-ATPase Bcs1 is involved in export of the folded Fe-S domain of Rip1 across the inner membrane and insertion of its transmembrane segment into an assembly intermediate of the cytochrome bc(1) complex. | 22017868 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
BCS1_YEAST
UniprotKB:
P32839
UniParc:
UPI0000126849
EMBL:
BK006938,
S47190,
U28373
EnsemblGenome:
YDR375C
KO:
sce:YDR375C
|
| Nucleutide sequences |
EMBL-CDS:
AAC09007.1,
DAA12217.1,
AAB64811.1
Gene_ORFName:
D9481.17
EnsemblGenome_TRS:
YDR375C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR375C
RefSeq:
NP_010663.1
|
| Others |
UniRef100:
UniRef100_P32839
UniRef90:
UniRef90_P32839
UniRef50:
UniRef50_P32839
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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