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851906 TFB1

851906

TFB1

TFIIH/NER complex subunit TFB1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition TFIIH/NER complex subunit TFB1

研究结论

Date Results Publications
2017-12-30 12:36:00 DNA opening is catalyzed by Ssl2, the dsDNA translocase subunit of the basal transcription factor TFIIH. ATP hydrolysis by Ssl2 opens a 6-base-pair (bp) bubble that grows to 13 bp in the presence of NTPs. These observations support a two-step model wherein ATP-dependent Ssl2 translocation leads to a 6-bp open complex that RNA polymerase II expands via NTP-dependent RNA transcription. 29106413
2012-10-06 10:21:00 Structure determination of a Rad2-Tfb1PH complex indicates that Rad2 binds to TFIIH using a similar motif as TFIIEalpha uses to bind TFIIH in the pre-initiation complex. 22373916
2010-01-21 00:00:00 NMR structure of the amino-terminal domain of the Tfb1 subunit 15772758
2010-01-21 00:00:00 The pleckstrin homology domain (residues 1-115) from the TFB1 subunit of TFIIH is sufficient for binding to the activation domain of herpes simplex virus protein VP16. 15909982

名称对应

Type IDs
Gene
UniProtKB-ID: TFB1_YEAST
UniprotKB: P32776
UniParc: UPI000005304B
EMBL: U28374, AY723790, M95750, BK006938
EnsemblGenome: YDR311W
KO: sce:YDR311W
Nucleutide sequences
EMBL-CDS: AAB64747.1, DAA12150.1, AAU09707.1, AAA35143.1
Gene_ORFName: D9740.3
EnsemblGenome_TRS: YDR311W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR311W
RefSeq: NP_010597.3
Others
UniRef100: UniRef100_P32776
UniRef90: UniRef90_P32776
UniRef50: UniRef50_P32776

全选

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