| Type | Description |
|---|---|
| Definition | Gic2p |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 10:27:00 | In yeast cells, Cdc42 polarization involves a positive feedback loop in which effectors called p21-activated kinases (PAKs) act to recruit a Cdc42-directed guanine nucleotide exchange factor (GEF), generating more GTP-Cdc42 in areas that already have GTP-Cdc42. The GTPase-interacting components (GICs) Gic1 and Gic2 are also Cdc42 effectors, and have been implicated in regulation of the actin and septin cytoskeleton. | 30566437 |
| 2013-02-23 11:19:00 | A novel regulatory input to Bni1p acting through the Cdc42p effector, Gic2p. | 22918946 |
| 2010-01-21 00:00:00 | phosphatidylinositol 4,5-bisphosphate and Cdc42 act in concert to regulate polarized localization and function of Gic2 during polarized cell growth in the budding yeast | 18387956 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GIC2_YEAST
UniprotKB:
Q06648
UniParc:
UPI000012B42E
EMBL:
U28374,
AY557791,
BK006938
EnsemblGenome:
YDR309C
KO:
sce:YDR309C
|
| Nucleutide sequences |
EMBL-CDS:
DAA12148.1,
AAB64745.1,
AAS56117.1
Gene_ORFName:
D9740.18
EnsemblGenome_TRS:
YDR309C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR309C
RefSeq:
NP_010595.1
|
| Others |
UniRef100:
UniRef100_Q06648
UniRef90:
UniRef90_Q06648
UniRef50:
UniRef50_Q06648
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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