Systematic analysis of complex genetic interactions.

Science     Elena Kuzmin , Benjamin VanderSluis , Wen Wang , Guihong Tan , Raamesh Deshpande , Yiqun Chen , Matej Usaj , Attila Balint , Mojca Mattiazzi Usaj , Jolanda van Leeuwen , Elizabeth N Koch , Carles Pons , Andrius J Dagilis , Michael Pryszlak , Jason Zi Yang Wang , Julia Hanchard , Margot Riggi , Kaicong Xu , Hamed Heydari , Bryan-Joseph San Luis , Ermira Shuteriqi , Hongwei Zhu , Nydia Van Dyk , Sara Sharifpoor , Michael Costanzo , Robbie Loewith , Amy Caudy , Daniel Bolnick , Grant W Brown , Brenda J Andrews , Charles Boone , Chad L Myers

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs.

PLoS Genet     Harley O'Connor Mount , Nicole M Revie , Robert T Todd , Kaitlin Anstett , Cathy Collins , Michael Costanzo , Charles Boone , Nicole Robbins , Anna Selmecki , Leah E Cowen

Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4.

G3 (Bethesda)     Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese

The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway.

J. Cell Biol.     Laura L Thomas , Aaron M N Joiner , J Christopher Fromme

GTPase cross talk regulates TRAPPII activation of Rab11 homologues during vesicle biogenesis.

J. Cell Biol.     Laura L Thomas , J Christopher Fromme

A global genetic interaction network maps a wiring diagram of cellular function.

Science     Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone

Target selection by natural and redesigned PUF proteins.

Proc. Natl. Acad. Sci. U.S.A.     Douglas F Porter , Yvonne Y Koh , Brett VanVeller , Ronald T Raines , Marvin Wickens

Trs20 is required for TRAPP III complex assembly at the PAS and its function in autophagy.

Traffic     David Taussig , Zhanna Lipatova , Nava Segev

The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway.

Proc. Natl. Acad. Sci. U.S.A.     Dongyan Tan , Yiying Cai , Juan Wang , Jinzhong Zhang , Shekar Menon , Hui-Ting Chou , Susan Ferro-Novick , Karin M Reinisch , Thomas Walz

Ypt1 recruits the Atg1 kinase to the preautophagosomal structure.

Proc. Natl. Acad. Sci. U.S.A.     Juan Wang , Shekar Menon , Akinori Yamasaki , Hui-Ting Chou , Thomas Walz , Yu Jiang , Susan Ferro-Novick