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851830 PRP28

851830

PRP28

mRNA splicing protein PRP28

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition mRNA splicing protein PRP28

研究结论

Date Results Publications
2019-04-27 10:16:00 Cellular fitness can be restored by compensatory mutations that alter either the splicing machinery per se or the Spt-Ada-Gcn5 acetyltransferase transcription co-activator complex in the cells with no Prp28. Biochemical and genetic analysis revealed that slowing down transcription compensates for splicing deficiency, which in turn boosts cellular fitness. 30297747
2015-04-04 11:48:00 The study demonstrated that yeast Prp28 is a bona fide RNA-dependent ATPase. 25303995
2014-03-01 10:02:00 The Prp8 suppressor partially corrected both the early assembly and later activation defects of prp28-1, supporting a role for this U5 snRNP protein in both the ATP-independent and ATP-dependent functions of Prp28. 24231520
2013-06-29 10:02:00 The subdomain linker in Prp28p plays important roles both in splicing efficiency and in proofreading of 5' splice site. 23462954

名称对应

Type IDs
Gene
UniProtKB-ID: PRP28_YEAST
UniprotKB: P23394
UniParc: UPI000005321A
EMBL: X56934, Z49701, BK006938
EnsemblGenome: YDR243C
KO: sce:YDR243C
Nucleutide sequences
EMBL-CDS: DAA12083.1, CAA89729.1, CAA40255.1
Gene_ORFName: YD8419.10C
EnsemblGenome_TRS: YDR243C_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR243C
RefSeq: NP_010529.3
Others
UniRef100: UniRef100_P23394
UniRef90: UniRef90_P23394
UniRef50: UniRef50_P23394

全选

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研究热度

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