| Type | Description |
|---|---|
| Definition | chromatin-silencing protein SIR4 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:44:00 | Esc1-interacting region of Sir4 is Dbf4-related H-BRCT domain | 30668669 |
| 2019-02-09 12:22:00 | A direct interaction between Ubp10 and the Sir2/4 sub-complex facilitates Ubp10 recruitment to chromatin via a co-assembly mechanism. | 29288197 |
| 2017-10-07 10:59:00 | the silencing factor Sir4, NE-associated Esc1, the SUMO E3 ligase Siz2, and the nuclear pore complex (NPC) protein Nup170-physically and functionally interact with one another and a subset of NPC components (nucleoporins or Nups). | 28883038 |
| 2017-09-09 10:47:00 | Repair of UV-induced DNA lesions in Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction. | 28334768 |
| 2017-05-27 11:16:00 | silencing requires Sir2, a highly-conserved NAD(+)-dependent histone deacetylase. At locations other than the rDNA, silencing also requires additional Sir proteins, Sir1, Sir3, and Sir4 that together form a repressive heterochromatin-like structure termed silent chromatin. | 27516616 |
| Type | IDs |
|---|---|
| Synonymous | ASD1, STE9, UTH2 |
| Gene |
UniProtKB-ID:
SIR4_YEAST
UniprotKB:
P11978
UniParc:
UPI0000052F71
EMBL:
Z48612,
M37249,
U13239,
BK006938
EnsemblGenome:
YDR227W
KO:
sce:YDR227W
|
| Nucleutide sequences |
EMBL-CDS:
DAA12069.1,
AAC33144.1,
AAA20881.1,
CAA88507.1
Gene_ORFName:
YD9934.12
EnsemblGenome_TRS:
YDR227W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR227W
RefSeq:
NP_010513.1
|
| Others |
UniRef100:
UniRef100_P11978
UniRef90:
UniRef90_P11978
UniRef50:
UniRef50_P11978
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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