| Type | Description |
|---|---|
| Definition | cohesin-loading factor complex subunit SCC2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:33:00 | A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules. | 31807710 |
| 2020-02-22 12:34:00 | The authors show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires opening the cohesin ring at its Smc3/Scc1 interface as well as the D loop of Smc1's ATPase. | 31225797 |
| 2019-10-19 12:34:00 | Here we reveal a dual role of RSC in cohesin loading. RSC acts as a chromatin receptor that recruits Scc2-Scc4 by a direct protein interaction independent of chromatin remodeling. In addition, chromatin remodeling is required to generate a nucleosome-free region that is the substrate for cohesin loading. | 30922844 |
| 2018-01-20 10:35:00 | Nipbl seems to have also additional roles, for instance as transcription factor.This chapter summarizes our current knowledge on kollerin function and the recent studies on the genomic localization of Scc2, highlighting and critically discussing controversial data. | 27797076 |
| 2017-12-09 11:15:00 | The role of Scc2 in cohesin loading | 27280786 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SCC2_YEAST
UniprotKB:
Q04002
UniParc:
UPI000013562D
EMBL:
Z46727,
BK006938,
Y14279
EnsemblGenome:
YDR180W
KO:
sce:YDR180W
|
| Nucleutide sequences |
EMBL-CDS:
CAA86687.1,
DAA12023.1,
CAA74656.1
Gene_ORFName:
YD9395.14
EnsemblGenome_TRS:
YDR180W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR180W
RefSeq:
NP_010466.3
|
| Others |
UniRef100:
UniRef100_Q04002
UniRef90:
UniRef90_Q04002
UniRef50:
UniRef50_Q04002
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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