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851754 HMO1

851754

HMO1

Hmo1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Hmo1p

研究结论

Date Results Publications
2021-01-23 13:00:00 Promotion of Hyperthermic-Induced rDNA Hypercondensation in Saccharomyces cerevisiae. 31980450
2017-11-18 12:38:00 Persistent induction of DNA double-strand breaks or mTORC1 inhibition by rapamycin results in reduced levels of HMO1 mRNA, but only in the presence of Tor1p. This down-regulation is accompanied by eviction of Ifh1p and recruitment of Crf1p, followed by concerted dissociation of Hmo1p and Tor1p. 28701348
2017-10-21 12:59:00 HMO1 appears to have evolved a unique linker histone-like function involving the ability to stabilize both conventional nucleosome arrays as well as DNA regions characterized by low nucleosome density or the presence of noncanonical nucleosomes. 27903656
2017-08-19 11:22:00 studied the genome-wide binding patterns of Nhp6, Hmo1 and the SWI/SNF complex, finding that most of gene promoters presenting high occupancy of this complex also display high enrichment of these HMG proteins. 28089519
2017-07-29 10:38:00 Hmo1p functions to control DNA end resection, thereby preventing error-prone A-EJ repair and directing repairs towards classical NHEJ. The very low efficiency of DSB repair in kuDeltahmo1Delta cells further suggests that excessive DNA resection is inhibitory for A-EJ. 28336179

名称对应

Type IDs
Synonymous HSM2
Gene
UniProtKB-ID: HMO1_YEAST
UniprotKB: Q03973
UniParc: UPI0000052FC7
EMBL: AY557680, BK006938, Z46727
EnsemblGenome: YDR174W
KO: sce:YDR174W
Nucleutide sequences
EMBL-CDS: AAS56006.1, CAA86679.1, DAA12016.1
Gene_ORFName: YD9395.07
EnsemblGenome_TRS: YDR174W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR174W
RefSeq: NP_010459.1
Others
UniRef100: UniRef100_Q03973
UniRef90: UniRef90_Q03973
UniRef50: UniRef50_Q03973

全选

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研究热度

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