| Type | Description |
|---|---|
| Definition | Arf family guanine nucleotide exchange factor SEC7 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 11:22:00 | results support a model in which the inter- and intramolecular interactions of the homology upstream of Sec7 ( HUS) box and the C terminus are necessary for the allosteric activation of Sec7. | 29514977 |
| 2017-01-14 10:36:00 | The DCB/HUS domain amplifies the ability of Sec7 to activate Arf1 on the membrane surface by facilitating membrane insertion of the Arf1 amphipathic helix. | 26765562 |
| 2014-12-20 10:45:00 | Sec7 is an effector of the Ypt1 and Ypt31/32 GTPases. | 25220393 |
| 2014-06-14 10:06:00 | Crystallographic, NMR spectrum and mutagenesis studies suggested that the loop>J motif with a key conserved residue Ile1010 modulates the fine conformation of Sec7 domain and thereby regulates its guanine exchange activity. | 24613384 |
| 2010-01-21 00:00:00 | analysis of the C-terminal sequence in the guanine nucleotide exchange factor Sec7 that mediates Golgi association and interaction with the Rsp5 ubiquitin ligase | 18832381 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SEC7_YEAST
UniprotKB:
P11075
UniParc:
UPI0000135756
EMBL:
BK006938,
Z46727,
Z47813,
J03918
EnsemblGenome:
YDR170C
KO:
sce:YDR170C
|
| Nucleutide sequences |
EMBL-CDS:
CAA87801.1,
DAA12011.1,
CAA86696.1,
AAB04031.1
Gene_ORFName:
YD9395.01C,
YD9489.05C
EnsemblGenome_TRS:
YDR170C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR170C
RefSeq:
NP_010454.3
|
| Others |
UniRef100:
UniRef100_P11075
UniRef90:
UniRef90_P11075
UniRef50:
UniRef50_P11075
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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