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851666 UBC13

851666

UBC13

E2 ubiquitin-conjugating protein UBC13

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition E2 ubiquitin-conjugating protein UBC13

研究结论

Date Results Publications
2018-10-06 10:15:00 Knockdown or conditional knockout of RNF8 or UBC13 in rodent cerebellar granule neurons robustly increases the number of parallel fiber presynaptic boutons and functional parallel fiber/Purkinje cell synapses. In contrast to the role of nuclear RNF8 in proliferating cells, RNF8 operates in the cytoplasm in neurons to suppress synapse differentiation. 29097665
2011-08-13 10:16:00 The authors demonstrate that in the absence of PCNA SUMOylation, Mms2-Ubc13 and Rad5 may, independently of each other, function in the stimulation of translesion DNA synthesis. 21362066
2010-10-23 10:04:00 Ubc13 appears to be essential for epidermal integrity in mice. 20663875
2010-01-21 12:36:00 Rad6-Rad18 and Ubc13-Mms2-Rad5 act sequentially and mediate proliferating cell nuclear antigen poly-ubiquitylation by stepwise addition of ubiquitin monomers. 19851286
2010-01-21 00:00:00 The structure reveals the key role of Mms2 in allowing selective insertion of Lys63 into the Ubc13 active site and suggests a molecular model for polyubiquitin chain elongation. 16980971

名称对应

Type IDs
Gene
UniProtKB-ID: UBC13_YEAST
UniprotKB: P52490
UniParc: UPI0000111EC7
EMBL: X99443, Z50111, BK006938
EnsemblGenome: YDR092W
KO: sce:YDR092W
Nucleutide sequences
EMBL-CDS: DAA11939.1, CAA67806.1, CAA90451.1
Gene_ORFName: YD6652.04
EnsemblGenome_TRS: YDR092W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR092W
RefSeq: NP_010377.3
Others
UniRef100: UniRef100_P52490
UniRef90: UniRef90_P52490
UniRef50: UniRef50_P35128

全选

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研究热度

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