| Type | Description |
|---|---|
| Definition | ubiquitin-specific protease DOA4 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-20 11:48:00 | Doa4 physically interacts with the ESCRT-III component Snf7 and preferentially cleaves Lys63-linked ubiquitin oligomers involved in membrane protein trafficking | 26427873 |
| 2013-11-02 11:08:00 | Binding of Vps20 to the Doa4 N-terminus inhibits a non-catalytic function of Doa4 that promotes ILV formation. | 23444383 |
| 2010-01-21 00:00:00 | This is the first demonstration of a physiologically important DUB (Doa4) subcellular localization signal and provides a striking example of the functional diversification of DUB paralogues by the evolution of alternative spatial signals. | 17145966 |
| 2010-01-21 00:00:00 | identified a protein designated Rfu1 (regulator of free ubiquitin chains 1), which regulates intracellular concentrations of monomeric ubiquitins; functions as an inhibitor of Doa4 | 19410548 |
| 2010-01-21 00:00:00 | Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies. | 17446860 |
| Type | IDs |
|---|---|
| Synonymous | DOS1, MUT4, NPI2, SSV7, UBP4 |
| Gene |
UniProtKB-ID:
UBP4_YEAST
UniprotKB:
P32571
UniParc:
UPI0000052EC2
EMBL:
Z74365,
U02518,
BK006938,
Z46796,
X84162,
L08070,
Z49209
EnsemblGenome:
YDR069C
KO:
sce:YDR069C
|
| Nucleutide sequences |
EMBL-CDS:
AAC48915.1,
CAA58985.1,
CAA89098.1,
DAA11915.1,
AAA35105.1,
CAA98887.1,
CAA86791.1
Gene_ORFName:
YD9609.23C,
YD8554.02C,
D4270
EnsemblGenome_TRS:
YDR069C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDR069C
RefSeq:
NP_010354.3
|
| Others |
UniRef100:
UniRef100_P32571
UniRef90:
UniRef90_P32571
UniRef50:
UniRef50_P32571
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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