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851623 DBF4

851623

DBF4

protein serine/threonine kinase activating protein DBF4

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition protein serine/threonine kinase activating protein DBF4

研究结论

Date Results Publications
2020-02-22 12:19:00 Using a Fkh1-dependent origin relocalization assay, the authors determine that execution of Dbf4-dependent kinase function, including Cdc45 loading, results in dynamic relocalization of a replication origin from the nuclear periphery to the interior in G1 phase. 31084713
2018-07-28 10:21:00 The authors propose that the timing of Eco1 phosphorylation, and potentially that of other DDK substrates, is determined in part by sequestration of DDK at unfired replication origins during S phase. 28918948
2018-02-10 10:34:00 Dbf4 interacts directly with Sld3 and promotes the recruitment of downstream limiting factors. 29330352
2017-07-08 12:53:00 The scaffold protein Rtt107, which binds the Mus81-Mms4 complex, interacts with Cdc7 and thereby targets Cdc7-Dbf4 and Cdc5 to the complex enabling full Mus81 activation. 28096179
2014-04-12 11:27:00 The Rad53-Dbf4 interaction is phosphorylation-independent and involves a novel non-canonical interface on the FHA1 domain. 24285546

名称对应

Type IDs
Synonymous DNA52, LSD7
Gene
UniProtKB-ID: DBF4_YEAST
UniprotKB: P32325
UniParc: UPI0000128EE5
EMBL: BK006938, X84162, M83539, X60279, Z74348, Z49209
EnsemblGenome: YDR052C
KO: sce:YDR052C
Nucleutide sequences
EMBL-CDS: CAA42819.1, CAA58969.1, AAA34573.1, CAA98869.1, CAA89082.1, DAA11899.1
Gene_ORFName: YD9609.07C, D4205
EnsemblGenome_TRS: YDR052C_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR052C
RefSeq: NP_010337.3
Others
UniRef100: UniRef100_P32325
UniRef90: UniRef90_P32325
UniRef50: UniRef50_P32325

全选

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研究热度

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