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851577 RAD61

851577

RAD61

Rad61p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Rad61p

研究结论

Date Results Publications
2020-06-06 10:16:00 The unique role of Rad61/Wapl is to promote non-crossover recombination by releasing [Pds5+Rec8]. For this effect, Rad61/Wapl probably acts to maintain homolog bias by preventing channeling into sister interactions. 31617566
2019-03-16 11:12:00 we confirmed that this release indeed accompanies the dissociation of acetylated Smc3 as well as Rec8 from meiotic chromosomes during late prophase-I. This release requires, in addition to PLK, the cohesin regulator, Wapl (Rad61/Wpl1 in yeast), and Dbf4-dependent Cdc7 kinase (DDK) 30605471
2016-09-24 12:13:00 Rad61/Wpl1 is required for efficient resolution of telomere clustering during meiosis I, indicating a positive effect of Rad61/Wpl1 on the cohesin function required for telomere dynamics. 26825462
2015-10-17 10:37:00 RAD61 deletion rescues the condensation defect, but importantly, neither the temperature sensitivity nor cohesion defects exhibited by pds5-1 mutant cells. 25986377

名称对应

Type IDs
Synonymous WPL1
Gene
UniProtKB-ID: RAD61_YEAST
UniprotKB: Q99359
UniParc: UPI000006B913
EMBL: Z74310, BK006938, X95966, Z48008
EnsemblGenome: YDR014W
KO: sce:YDR014W
Nucleutide sequences
EMBL-CDS: CAA88074.1, DAA11860.1, CAA65206.1, CAA98834.1
Gene_ORFName: PZB647
EnsemblGenome_TRS: YDR014W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDR014W
RefSeq: NP_010297.1
Others
UniRef100: UniRef100_Q99359
UniRef90: UniRef90_Q99359
UniRef50: UniRef50_Q99359

全选

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