| Type | Description |
|---|---|
| Definition | glutathione-disulfide reductase GRX6 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 01:48:00 | Crystal structure of Grx6 in complex with a glutathione-coordinated [2Fe-2S] cluster has been presented. | 27710937 |
| 2015-08-22 10:06:00 | A specific function influenced by Grx6 activity is the homeostasis of intracellular calcium. Grx6-deficient mutants have reduced levels of calcium in the ER lumen, whereas accumulation occurs at the cytosol from extracellular sources. | 25355945 |
| 2010-05-10 11:08:00 | Compared to the classic dithiol glutaredoxin Grx1, Grx6 has a lower glutathione disulfide reductase activity but a higher glutathione S-transferase activity. | 20347849 |
| 2010-01-21 00:00:00 | Grx6 and Grx7 do not play a general role in the oxidative folding of proteins in the early secretory pathway but rather counteract the oxidation of specific thiol groups in substrate proteins. | 18400945 |
| 2010-01-21 00:00:00 | S. pombe cells harboring plasmid pFGRX6 containing the Grx6 gene had about 1.3-fold elevated Grx activity in the exponential phase, and grew better than the control cells under some stressful conditions. | 18182845 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GLRX6_YEAST
UniprotKB:
Q12438
UniParc:
UPI0000036C2D
EMBL:
Z48432,
BK006938,
Z74059
EnsemblGenome:
YDL010W
KO:
sce:YDL010W
|
| Nucleutide sequences |
EMBL-CDS:
CAA98567.1,
DAA11838.1,
CAA88349.1
Gene_ORFName:
D2890
EnsemblGenome_TRS:
YDL010W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDL010W
RefSeq:
NP_010274.1
|
| Others |
UniRef100:
UniRef100_Q12438
UniRef90:
UniRef90_Q12438
UniRef50:
UniRef50_Q12438
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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