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851545 CDC7

851545

CDC7

serine/threonine protein kinase CDC7

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition serine/threonine protein kinase CDC7

研究结论

Date Results Publications
2019-05-25 12:06:00 Cdc7p regulates replication-coupled histone modification via a CAC1-dependent mechanism involving H4 K16ac deposition. 30728156
2019-03-16 11:12:00 we confirmed that this release indeed accompanies the dissociation of acetylated Smc3 as well as Rec8 from meiotic chromosomes during late prophase-I. This release requires, in addition to PLK, the cohesin regulator, Wapl (Rad61/Wpl1 in yeast), and Dbf4-dependent Cdc7 kinase (DDK) 30605471
2018-10-13 10:29:00 main conclusion from our studies is that Cdc7 kinase is found at many locations in the genome, but is enriched at functional origins of replication 29134273
2018-07-28 10:21:00 The authors propose that the timing of Eco1 phosphorylation, and potentially that of other DDK substrates, is determined in part by sequestration of DDK at unfired replication origins during S phase. 28918948
2018-06-23 10:39:00 Cdc7 is loosely bound to chromatin during G1. At the G1/S transition, Cdc7 binding to chromatin is increased and stabilized, preferentially at sites that may become replication origins. 28924058

名称对应

Type IDs
Synonymous LSD6, SAS1
Gene
UniProtKB-ID: CDC7_YEAST
UniprotKB: P06243
UniParc: UPI000012725A
EMBL: X14164, Z74065, X15362, M12624, BK006938, Z48432
EnsemblGenome: YDL017W
KO: sce:YDL017W
Nucleutide sequences
EMBL-CDS: CAA98574.1, CAA32369.1, DAA11833.1, AAA34485.1, CAA88342.1, CAA33420.1, CAA32370.1
Gene_ORFName: D2855
EnsemblGenome_TRS: YDL017W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDL017W
RefSeq: NP_010267.3
Others
UniRef100: UniRef100_P06243
UniRef90: UniRef90_P06243
UniRef50: UniRef50_P06243

全选

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研究热度

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