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851542 RPN4

851542

RPN4

stress-regulated transcription factor RPN4

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition stress-regulated transcription factor RPN4

研究结论

Date Results Publications
2020-03-21 10:10:00 The authors identify the proteasome biogenesis regulator Rpn4 and show that it cooperates with the unfolded protein response. Rpn4 abundance increases during endoplasmic reticulum stress, first by a post-transcriptional, then by a transcriptional mechanism. 30865586
2017-01-14 10:20:00 Rpn4 induces TMC1 transcription in response to misfolded proteins. However, this response is counteracted by rapid proteasome-dependent degradation of Tmc1, which serves to normalize Tmc1 protein levels after induction 27226598
2015-05-23 11:27:00 Rpn4-responsive elements in genes related to proteasome functions 25747386
2015-04-18 11:48:00 under the methyl methanesulfonate stress Rpn4 promotes the regulation of several genes involved in DNA repair, antioxidant response and glucose metabolism. 25842837
2012-05-12 10:04:00 the ubiquitin-independent degradation of Rpn4 requires the 19S regulatory particle. 22349505

名称对应

Type IDs
Synonymous SON1, UFD5
Gene
UniProtKB-ID: RPN4_YEAST
UniprotKB: Q03465
UniParc: UPI000013464A
EMBL: Z48432, BK006938, L00928, Z74068, AY723763
EnsemblGenome: YDL020C
KO: sce:YDL020C
Nucleutide sequences
EMBL-CDS: AAA35067.1, DAA11830.1, AAU09680.1, CAA98579.1, CAA88339.1
Gene_ORFName: D2840
EnsemblGenome_TRS: YDL020C_mRNA
Protein sequencees
EnsemblGenome_PRO: YDL020C
RefSeq: NP_010264.3
Others
UniRef100: UniRef100_Q03465
UniRef90: UniRef90_Q03465
UniRef50: UniRef50_Q03465

全选

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研究热度

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