| Type | Description |
|---|---|
| Definition | NAD-dependent histone deacetylase SIR2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence. | 33370275 |
| 2020-08-29 12:48:00 | Sir2 mitigates an intrinsic imbalance in origin licensing efficiency between early- and late-replicating euchromatin. | 32513739 |
| 2020-01-11 11:35:00 | It was believed the only role for Saccharomyces cerevisiae Sir2 in mating-type switching was silencing HML and HMR. Study shows that Sir2 also regulates expression of a small gene (RDT1) in the cis-acting DNA element called the recombination enhancer that is activated during mating-type switching. | 31461456 |
| 2019-12-07 10:08:00 | In this mini-review, we propose a "Musical Chair" model for rDNA copy counting as mediated by UAF and Sir2. The model describes how a straightforward molecular mechanism can account for the "cellular memory" of the proper rDNA copy number | 30904990 |
| 2019-02-09 12:22:00 | A direct interaction between Ubp10 and the Sir2/4 sub-complex facilitates Ubp10 recruitment to chromatin via a co-assembly mechanism. | 29288197 |
| Type | IDs |
|---|---|
| Synonymous | MAR1 |
| Gene |
UniProtKB-ID:
SIR2_YEAST
UniprotKB:
P06700
UniParc:
UPI0000052F70
EMBL:
Z74090,
BK006938,
Z71781,
X01419
EnsemblGenome:
YDL042C
KO:
sce:YDL042C
|
| Nucleutide sequences |
EMBL-CDS:
CAA96447.1,
CAA25667.1,
CAA98600.1,
DAA11814.1
Gene_ORFName:
D2714
EnsemblGenome_TRS:
YDL042C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDL042C
RefSeq:
NP_010242.1
|
| Others |
UniRef100:
UniRef100_P06700
UniRef90:
UniRef90_P06700
UniRef50:
UniRef50_P06700
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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