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851495 UBC9

851495

UBC9

E2 SUMO-conjugating protein UBC9

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition E2 SUMO-conjugating protein UBC9

研究结论

Date Results Publications
2019-10-05 10:55:00 Replacement of proline with leucine at position 123 induces a switch from the preferential addition of SUMO to lysine residues in unstructured sites to acceptor lysines embedded in secondary structures. This causes alterations in SUMO chain linkages. 30574775
2013-08-31 12:04:00 Ubc9 sumoylation is a key event for meiotic synaptonemal complex formation. SUMO Ubc9 enhances catalysis by binding and orienting donor SUMO charged Ubc9. 23644018
2010-01-21 00:00:00 analysis of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p 17475278
2010-01-21 00:00:00 These findings establish a functional interaction between N-terminal and substrate-binding domains of Ubc9 and distinguish the activities of E3 ligases Siz1 and Siz2 in regulating cellular responses to genotoxic stress. 16782883
2010-01-21 00:00:00 The crystal structure of sumoylated Ubc9 demonstrates how the newly created binding interface can provide a gain in affinity otherwise provided by E3 ligases. 18691969

名称对应

Type IDs
Gene
UniProtKB-ID: UBC9_YEAST
UniprotKB: P50623
UniParc: UPI000013796C
EMBL: Z74112, BK006938, X82538
EnsemblGenome: YDL064W
KO: sce:YDL064W
Nucleutide sequences
EMBL-CDS: DAA11793.1, CAA98629.1, CAA57888.1
EnsemblGenome_TRS: YDL064W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDL064W
RefSeq: NP_010219.1
Others
UniRef100: UniRef100_P50623
UniRef90: UniRef90_P50623
UniRef50: UniRef50_P50623

全选

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研究热度

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