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851475 SUB2

851475

SUB2

ATP-dependent RNA helicase SUB2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ATP-dependent RNA helicase SUB2

研究结论

Date Results Publications
2021-04-03 13:34:00 Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. 33191913
2018-02-10 11:31:00 Both THO and Yra1-C stimulated Sub2's intrinsic ATPase activity. The authors propose that THO surveys common landmarks in each nuclear mRNP to localize Sub2 for targeted loading of Yra1. 28059701
2013-11-16 11:54:00 RNA helicase Sub2p mutation is associated with growth, mRNA export, and genomic stability. 23962665
2011-10-08 12:05:00 This work establishes a genome-wide function for THO-Sub2 in transcription elongation and mRNP biogenesis that function to prevent the accumulation of transcription-mediated replication obstacles, including R-loops. 21701562
2010-01-21 00:00:00 Data suggests that the THO complex/Sub2p function is required to coordinate events leading to the acquisition of export competence at a step that follows commitment to 3'-processing. 18957205

名称对应

Type IDs
Gene
UniProtKB-ID: SUB2_YEAST
UniprotKB: Q07478
UniParc: UPI000013617A
EMBL: AY692907, BK006938, Z74132
EnsemblGenome: YDL084W
KO: sce:YDL084W
Nucleutide sequences
EMBL-CDS: DAA11775.1, AAT92926.1, CAA98650.1
EnsemblGenome_TRS: YDL084W_mRNA
Protein sequencees
EnsemblGenome_PRO: YDL084W
RefSeq: NP_010199.1
Others
UniRef100: UniRef100_Q07478
UniRef90: UniRef90_Q07478
UniRef50: UniRef50_Q07478

全选

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研究热度

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