| Type | Description |
|---|---|
| Definition | dolichyl-phosphate-mannose-protein mannosyltransferase PMT1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-05 10:54:00 | Maximal Pmt1 expression depends on both, transcriptional activation of Pmt1 under cell stress conditions as well as elevated translation efficiency mediated by Bfr1. The fine-tuned coordination of Pmt1 protein abundance with ER stress further implies that O-mannosylation and protein folding must be balanced to ensure functionality of canonical target proteins and unfolded protein O-mannosylation. | 31835530 |
| 2020-02-22 10:53:00 | Cryo-EM structures of the Saccharomyces cerevisiae Pmt1-Pmt2 complex bound to a donor and an acceptor peptide at 3.2-A resolution, showing that each subunit contains 11 transmembrane helices and a lumenal beta-trefoil fold termed the MIR domain. The transmembrane domains of Pmt1 and Pmt2 share a structural fold with the catalytic subunits of oligosaccharyltransferases. | 31285605 |
| 2017-04-29 12:22:00 | Translational effects of Dom34 required the 5'-UTR of the PMT1 transcript, which bound recombinant Dom34 directly at a CA/AC-rich sequence and regulated in vitro translation. Polysomal profiling revealed that Dom34 stimulates general translation moderately, but that it is especially required for translation of transcripts encoding Pmt isoforms 1, 4 and 6. | 27768707 |
| 2016-01-16 11:10:00 | PMT1 deficiency enhances basal activity of the ER UPR and extends the RLS of yeast mother cells through a mechanism that requires both IRE1 and HAC1. | 25936926 |
| 2014-05-31 11:21:00 | Pmt1-Pmt2 Complexes Are Associated with the Translocon Complex in Vivo. | 24519942 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PMT1_YEAST
UniprotKB:
P33775
UniParc:
UPI000011DD21
EMBL:
Z74144,
X95644,
BK006938,
L19169
EnsemblGenome:
YDL095W
KO:
sce:YDL095W
|
| Nucleutide sequences |
EMBL-CDS:
CAA64917.1,
AAA02928.1,
DAA11764.1,
CAA98663.1
Gene_ORFName:
D2390
EnsemblGenome_TRS:
YDL095W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YDL095W
RefSeq:
NP_010188.1
|
| Others |
UniRef100:
UniRef100_P33775
UniRef90:
UniRef90_P33775
UniRef50:
UniRef50_P33775
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员