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8513 LIPF

8513

LIPF

lipase F, gastric type

protein-coding

Homo sapiens

基因描述

Type Description
Definition lipase F, gastric type

研究结论

Date Results Publications
2017-11-25 13:39:00 site-directed mutagenesis the role of three key residues (K4, E225, R229) involved in salt bridges stabilizing the lid domain that controls the access to the active site and is part of the interfacial recognition site. Their substitution has an impact on the pH-dependent activity of rHGL and its relative activities on medium and long chain triglycerides. 28694218
2017-03-18 12:41:00 LIPFDGKA might serve as a potential possible biomarkers for diagnosis of gastric cancer, and their downregulation may bring new perspective into the investigation of gastric cancer prognosis 27498782
2016-09-10 10:57:00 In patients with intrahepatic cholestasis of pregnancy, there was no elevation in LIPF mRNA in maternal circulation compared with controls. 25059952
2012-03-03 11:15:00 Recombinant human gastric lipase (hGL) was transiently expressed in Nicotiana benthamiana leaves using the CPMV-HT expression system. 21945702
2011-01-01 11:14:00 insights into the domain movements 20965171

名称对应

Type IDs
Synonymous GL, HGL, HLAL
Gene
UniProtKB-ID: LIPG_HUMAN
UniprotKB: P07098
UniParc: UPI00003741B2, UPI0001E92A2A, UPI000045896D, UPI000002B8F3
EMBL: BC112272, BC113711, AK301310, AK312940, AK301320, AL358532, CH471066, AL833751, AY631869, X05997
Ensembl: ENSG00000182333
KO: hsa:8513
Nucleutide sequences
EMBL-CDS: CAA29414.1, AAI12273.1, BAH13457.1, AAI13712.1, EAW50162.1, BAG35782.1, CAA29413.1, CAH56244.1, BAH13459.1, AAT38115.1
Ensembl_TRS: ENST00000608620, ENST00000394375, ENST00000355843, ENST00000238983
Protein sequencees
Ensembl_PRO: ENSP00000477140, ENSP00000238983, ENSP00000377900, ENSP00000348101
RefSeq: XP_011538613.1, NP_001185758.1, NP_001185759.1, NP_004181.1, NP_001185757.1
Others
UniRef100: UniRef100_P07098
UniRef90: UniRef90_P07098
UniRef50: UniRef50_P07098
UniGene: Hs.523130
CCDS: CCDS55719.1, CCDS65896.1, CCDS7389.1, CCDS55718.1

全选

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