| Type | Description |
|---|---|
| Definition | DNA-dependent ATPase FUN30 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Role of the ATP-dependent chromatin remodeling enzyme Fun30/Smarcad1 in the regulation of mRNA splicing. | 32234239 |
| 2018-01-13 12:18:00 | Budding yeast Fun30 and human SMARCAD1 are cell cycle-regulated by interaction with the DNA double strand break-localized scaffold protein Dpb11/TOPBP1, respectively. In yeast, this protein assembly additionally comprises the 9-1-1 damage sensor, is involved in localizing Fun30 to damaged chromatin, and thus is required for efficient long-range resection of DNA double strand breaks. | 28063255 |
| 2017-08-12 12:07:00 | Fun30 acts to down regulate Rad9-dependent DNA damage checkpoint triggered by CPT or MMS, but does not affect Rad9-independent intra-S phase replication checkpoint induced by MMS or HU. It supports the notion that Fun30 contributes to cellular response to DSBs by preventing excessive DNA damage checkpoint activation in addition to its role in facilitating DNA end resection. | 28089177 |
| 2016-08-27 10:22:00 | Cdk1 and multiple cyclins become highly enriched at DSBs and that the recruitment of Cdk1 and cyclins Clb2 and Clb5 ensures optimal Fun30 phosphorylation and checkpoint activation. | 26801641 |
| 2013-11-02 10:18:00 | These results define a role for Fun30 in the regulation of transcription and indicate that Fun30 remodels chromatin at the 5' end of genes by sliding promoter-proximal nucleosomes. | 23779104 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FUN30_YEAST
UniprotKB:
P31380
UniParc:
UPI0000052EBB
EMBL:
BK006935,
L05146
EnsemblGenome:
YAL019W
KO:
sce:YAL019W
|
| Nucleutide sequences |
EMBL-CDS:
DAA06969.1,
AAC04938.1
Gene_ORFName:
YAL001
EnsemblGenome_TRS:
YAL019W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YAL019W
RefSeq:
NP_009383.1
|
| Others |
UniRef100:
UniRef100_P31380
UniRef90:
UniRef90_P31380
UniRef50:
UniRef50_P31380
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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