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851207 DRS2

851207

DRS2

aminophospholipid-translocating P4-type ATPase DRS2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition aminophospholipid-translocating P4-type ATPase DRS2

研究结论

Date Results Publications
2020-08-15 16:05:00 The Drs2 PS flippase activity is required to support neo1Delta any1Delta viability. 30824614
2019-10-12 12:26:00 cryo-electron microscopy structure of the P4-ATPase Drs2p-Cdc50p; three structures are presented that represent the complex in an autoinhibited, an intermediate and a fully activated state 31243363
2017-07-15 12:02:00 activation of the Drs2p-Cdc50p flippase follows a multistep mechanism, with preliminary release of a number of constraints, possibly through the binding of regulatory proteins in the trans-Golgi network, followed by full activation by PI4P 28302728
2016-10-01 10:31:00 Deletion of KES1 suppresses plasma membrane-missorting defects and the accumulation of intracellular ergosterol in drs2 mutants. 26466678
2016-09-24 12:08:00 we describe the overexpression of a yeast lipid flippase complex, namely the P4-ATPase Drs2p and its associated subunit Cdc50p, in a coordinated manner. 26695021

名称对应

Type IDs
Synonymous FUN38, SWA3
Gene
UniProtKB-ID: ATC3_YEAST
UniprotKB: P39524
UniParc: UPI0001F7BD26
EMBL: U12980, BK006935, L01795
EnsemblGenome: YAL026C
KO: sce:YAL026C
Nucleutide sequences
EMBL-CDS: AAA16891.1, AAC05006.1, DAA06962.2
Gene_ORFName: FUN38
EnsemblGenome_TRS: YAL026C_mRNA
Protein sequencees
EnsemblGenome_PRO: YAL026C
RefSeq: NP_009376.2
Others
UniRef100: UniRef100_P39524
UniRef90: UniRef90_P39524
UniRef50: UniRef50_P39524

全选

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