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851193 CDC19

851193

CDC19

pyruvate kinase CDC19

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition pyruvate kinase CDC19

研究结论

Date Results Publications
2019-02-09 11:59:00 Cdc19 aggregation in vitro is governed by protein quaternary structure. Cdc19 aggregates share several structural features with pathological amyloids formed by human insulin and the Alzheimer's disease-associated ABETA42 peptide. 29853641
2017-10-28 12:11:00 Reversible aggregation protects Cdc19 from stress-induced degradation, thereby allowing cell cycle restart after stress. 28846094
2017-03-11 11:38:00 Data show that the pyruvate-forming enzyme Pyk1 was tethered to heterologous pyruvate-converting enzymes, lactate dehydrogenase and alpha-acetolactate synthase, to producelactic acid and 2,3-butanediol, respectively. 27052099
2012-05-26 10:46:00 CDC19 allele from the Htg(+)Saccharomyces cereviseae strain had 7 base changes resulting in silent mutations in its coding region. The base changes increased pyruvate kinase activity and activation of energy metabolism to maintain cellular homeostasis. 21459167
2010-01-21 00:00:00 In yeast the major phosphorylation site of Pyk1 is Ser22. Phosphorylation of Ser22 leads to a Pyk1 enzyme that is more active in the absence of fructose 1,6-bisphosphate 16426231

名称对应

Type IDs
Synonymous PYK1
Gene
UniProtKB-ID: KPYK1_YEAST
UniprotKB: P00549
UniParc: UPI000011038E
EMBL: V01321, AY949880, AY949883, AY949878, AY949881, AY693107, AY949890, AY949863, AY949870, BK006935, AY949872, AY949869, AY949879, AY949866, AY949889, AY949882, AY949873, AY949885, AY949862, AY949864, AY949865, AY949876, AY949868, U12980, AY949871, AY949875, X14400, AY949888, AY949884, AY949874, AY949886, AY949887, AY949867, AY949877
EnsemblGenome: YAL038W
KO: sce:YAL038W
Nucleutide sequences
EMBL-CDS: AAY27289.1, AAY27286.1, DAA06948.1, AAY27278.1, AAY27265.1, CAA32573.1, AAT93126.1, CAA24631.1, AAY27277.1, AAY27284.1, AAY27272.1, AAY27280.1, AAY27271.1, AAY27267.1, AAY27283.1, AAY27276.1, AAY27290.1, AAY27270.1, AAY27275.1, AAY27279.1, AAY27287.1, AAY27281.1, AAY27292.1, AAY27282.1, AAY27291.1, AAY27288.1, AAY27268.1, AAY27274.1, AAY27266.1, AAY27273.1, AAY27264.1, AAC04993.1, AAY27285.1, AAY27269.1
EnsemblGenome_TRS: YAL038W_mRNA
Protein sequencees
EnsemblGenome_PRO: YAL038W
RefSeq: NP_009362.1
Others
UniRef100: UniRef100_P00549
UniRef90: UniRef90_P00549
UniRef50: UniRef50_P00549

全选

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研究热度

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