| Type | Description |
|---|---|
| Definition | Rho family guanine nucleotide exchange factor CDC24 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-07 10:17:00 | Using optogenetics, the authors probe yeast polarization and find that local recruitment of Cdc24 or Bem1 is sufficient to induce polarization by triggering self-sustaining Cdc42 activity. | 28682236 |
| 2017-11-26 01:38:00 | Biochemical analysis confirmed that this mutation disturbs the interaction with Bem1 but not the fold of the protein. The larger dataset obtained by NGS achieved a more complete representation of the bipartite interaction interface of Cdc24. | 27402358 |
| 2012-04-14 10:29:00 | We propose that the NH2-terminal region unmasks the DH and PB1 domains, leading to the activation of Cdc42 and interaction with Bem1, respectively, to initiate cell polarization | 22117027 |
| 2010-01-21 00:00:00 | These data support roles for Boi2p, Ent2p, Hua1p, Tos2p, and for Cdc24p phosphorylation in targeting Cdc24p to growth sites. | 19782078 |
| 2010-01-21 00:00:00 | Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae | 15657049 |
| Type | IDs |
|---|---|
| Synonymous | CLS4 |
| Gene |
UniProtKB-ID:
CDC24_YEAST
UniprotKB:
P11433
UniParc:
UPI0000052E60
EMBL:
BK006935,
U12980,
M16809
EnsemblGenome:
YAL041W
KO:
sce:YAL041W
|
| Nucleutide sequences |
EMBL-CDS:
AAC04990.1,
AAA82871.1,
DAA06945.1
EnsemblGenome_TRS:
YAL041W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YAL041W
RefSeq:
NP_009359.1
|
| Others |
UniRef100:
UniRef100_P11433
UniRef90:
UniRef90_P11433
UniRef50:
UniRef50_P11433
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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