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851173 SST2

851173

SST2

GTPase-activating protein SST2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition GTPase-activating protein SST2

研究结论

Date Results Publications
2017-06-10 11:47:00 Results suggest that the G-protein-coupled receptor, Ste2 binds the inhibitory G-protein signaling, Sst2 forming a complex with antagonistic functions. 28034910
2016-09-24 12:03:00 Results reveal that a regulator of G protein signaling can also regulate the G protein-coupled receptor. Whereas Sst2 negatively regulates G protein signaling, it acts in a positive manner to promote receptor retention at the growing edge. 26310439
2014-10-04 11:44:00 Sst2 limits variability in transcription and morphogenesis in response to pheromone stimulation. 24954905
2010-01-21 00:00:00 These findings suggest that Sst2 is the principal regulator of Gpa1-mediated signaling in vivo but that other proteins also contribute in distinct ways to pathway regulation. 16467474
2010-01-21 00:00:00 We demonstrate that DEP domains in Sst2 mediate binding to its cognate GPCR (Ste2). DEP-domain-mediated tethering promotes downregulation by placing the RGS protein in proximity to its substrate. 16990133

名称对应

Type IDs
Gene
UniProtKB-ID: SST2_YEAST
UniprotKB: P11972
UniParc: UPI000013603F
EMBL: BK006945, M18105, U22382
EnsemblGenome: YLR452C
KO: sce:YLR452C
Nucleutide sequences
EMBL-CDS: DAA09752.1, AAB67534.1, AAA35104.1
Gene_ORFName: L9324.9
EnsemblGenome_TRS: YLR452C_mRNA
Protein sequencees
EnsemblGenome_PRO: YLR452C
RefSeq: NP_013557.1
Others
UniRef100: UniRef100_P11972
UniRef90: UniRef90_P11972
UniRef50: UniRef50_P11972

全选

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研究热度

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