| Type | Description |
|---|---|
| Definition | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 |
| Date | Results | Publications |
|---|---|---|
| 2013-05-18 12:03:00 | Nsg1-mediated stabilization of Hmg2 and the Nsg1-Hmg2 interaction required the early sterol lanosterol. | 23306196 |
| 2011-10-01 12:07:00 | The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2. | 21628456 |
| 2010-11-27 10:25:00 | In the K6R substituted Hmg2 mutant, the squalene content was approximately 20-fold higher than in the wild-type EGY48 parental strain and ERG6 deletion did not further enhance squalene accumulation. | 20550581 |
| 2010-01-21 00:00:00 | results show that farnesol causes Hmg2p to undergo a change to a less folded structure | 15635451 |
| 2010-01-21 00:00:00 | GGPP is the FPP-derived regulator of Hmg2p ubiquitination. | 19776008 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HMDH2_YEAST
UniprotKB:
P12684
UniParc:
UPI000012C9D2
EMBL:
U22382,
AY692800,
M22255,
BK006945
EnsemblGenome:
YLR450W
KO:
sce:YLR450W
|
| Nucleutide sequences |
EMBL-CDS:
AAT92819.1,
DAA09750.1,
AAA34677.1,
AAB67527.1
Gene_ORFName:
L9324.2
EnsemblGenome_TRS:
YLR450W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR450W
RefSeq:
NP_013555.1
|
| Others |
UniRef100:
UniRef100_P12684
UniRef90:
UniRef90_P12684
UniRef50:
UniRef50_P12684
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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