| Type | Description |
|---|---|
| Definition | chromatin-silencing protein SIR3 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:48:00 | Direct interaction of Sir3 with O-acetyl-ADP-ribose promotes the further spreading of Sir3 along telomeres. | 31366171 |
| 2018-07-07 12:00:00 | Yeast Sir2 and Sir3 heterochromatin proteins directly modify the local chromatin environment of euchromatic DNA replication origins. | 29795547 |
| 2017-11-11 12:13:00 | Here, the authors analyze binding of the Sir proteins to reconstituted mono-, di-, tri-, and tetra-nucleosomal chromatin templates and show that key Sir-Sir interactions bridge only sites on different nucleosomes but not sites on the same nucleosome, and are therefore 'interrupted' with respect to sites on the same nucleosome. | 27835568 |
| 2017-09-09 10:47:00 | Repair of UV-induced DNA lesions in Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction. | 28334768 |
| 2017-05-27 11:16:00 | silencing requires Sir2, a highly-conserved NAD(+)-dependent histone deacetylase. At locations other than the rDNA, silencing also requires additional Sir proteins, Sir1, Sir3, and Sir4 that together form a repressive heterochromatin-like structure termed silent chromatin. | 27516616 |
| Type | IDs |
|---|---|
| Synonymous | CMT1, MAR2, STE8 |
| Gene |
UniProtKB-ID:
SIR3_YEAST
UniprotKB:
P06701
UniParc:
UPI00001359A9
EMBL:
X01420,
AY693157,
U21094,
BK006945
EnsemblGenome:
YLR442C
KO:
sce:YLR442C
|
| Nucleutide sequences |
EMBL-CDS:
DAA09743.1,
CAA25668.1,
AAT93176.1,
AAB67522.1
Gene_ORFName:
L9753.10
EnsemblGenome_TRS:
YLR442C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR442C
RefSeq:
NP_013547.3
|
| Others |
UniRef100:
UniRef100_P06701
UniRef90:
UniRef90_P06701
UniRef50:
UniRef50_P06701
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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