| Type | Description |
|---|---|
| Definition | MCM DNA helicase complex subunit MCM5 |
| Date | Results | Publications |
|---|---|---|
| 2010-11-06 10:34:00 | The Mcm ATPase active sites that flank Mcm2/5 (i.e. Mcm5/3 and 6/2) modulate the biochemical activities of the putative Mcm2/5 gate. | 20484375 |
| 2010-01-21 00:00:00 | A domain-push model is proposed to explain the bypass activity of mutant proline62leucine BOB1, which has a major effect on helicase activity, but no significant impact on DNA binding or ATPase of Methanobacterium thermoautotrophicum MCM gene. | 16401076 |
| 2010-01-21 00:00:00 | Mcm5 protein has a positive role in origin binding, which requires coordination by all six Mcm2-7 subunits in the hexamer. | 18660534 |
| 2010-01-21 00:00:00 | DNA runs through a central channel in the double hexamer, and, once loaded, Mcm2-7 can slide passively along double-stranded DNA. | 19896182 |
| 2010-01-21 00:00:00 | Conclusions predict a structural discontinuity between Mcm2 and Mcm5 and demonstrate that in contrast to other hexameric helicases, the six Mcm2-7 active sites are functionally distinct. | 18662997 |
| Type | IDs |
|---|---|
| Synonymous | BOB1, CDC46 |
| Gene |
UniProtKB-ID:
MCM5_YEAST
UniprotKB:
P29496
UniParc:
UPI00000531AD
EMBL:
BK006945,
U09242,
U17245
EnsemblGenome:
YLR274W
KO:
sce:YLR274W
|
| Nucleutide sequences |
EMBL-CDS:
AAB67364.1,
DAA09587.1,
AAA18027.1
Gene_ORFName:
L9328.1
EnsemblGenome_TRS:
YLR274W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR274W
RefSeq:
NP_013376.1
|
| Others |
UniRef100:
UniRef100_P29496
UniRef90:
UniRef90_P29496
UniRef50:
UniRef50_P29496
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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