| Type | Description |
|---|---|
| Definition | DNA topoisomerase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:56:00 | Deletion of ULS1 confers damage tolerance in sgs1 mutants through a Top3-dependent D-loop mediated fork restart pathway | 31005681 |
| 2017-12-02 11:57:00 | Although Top3 and Sgs1 interact without sumoylation, sumoylated forms of Sgs1, particularly those containing K621 conjugates, are preferentially enriched in complexes with Top3. | 27373152 |
| 2016-06-04 10:18:00 | Our data are consistent with a redundant role of Top2 and Sgs1 together with Top3 (Sgs1-Top3) in replication fork merging at rDNA barriers. | 26630413 |
| 2015-04-25 12:17:00 | The strand-passage activity of Top3-Rmi1 is required for all known functions of Sgs1 in meiotic recombination, including channeling JMs into physiological crossover and noncrossover pathways, and suppression of non-allelic recombination. | 25699709 |
| 2015-04-25 12:17:00 | Top3-Rmi1 acts in all meiotic recombination functions previously associated with Sgs1, most notably as an early recombination intermediate chaperone, promoting regulated crossover and noncrossover recombination. | 25699707 |
| Type | IDs |
|---|---|
| Synonymous | EDR1 |
| Gene |
UniProtKB-ID:
TOP3_YEAST
UniprotKB:
P13099
UniParc:
UPI0000036C75
EMBL:
BK006945,
M24939,
U19027
EnsemblGenome:
YLR234W
KO:
sce:YLR234W
|
| Nucleutide sequences |
EMBL-CDS:
AAB67406.1,
DAA09550.1,
AAA35161.1
Gene_ORFName:
L8083.3
EnsemblGenome_TRS:
YLR234W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR234W
RefSeq:
NP_013335.1
|
| Others |
UniRef100:
UniRef100_P13099
UniRef90:
UniRef90_P13099
UniRef50:
UniRef50_P13099
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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