| Type | Description |
|---|---|
| Definition | Est1p |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 10:22:00 | Est1 binds two adjacent, separate patches of Cdc13 with distinct pockets. The N-terminal interface of Cdc13-Est1 backstops TLC1-Ku-Sir4 to recruit telomerase. The C-terminal interface of Cdc13-Est1 is crucial for telomere maintenance in vivo. | 29290466 |
| 2015-08-01 12:02:00 | Recruitment of Est1 to telomeres via a Cdc13-Est1 fusion is sufficient to bypass the role of Ku in promoting telomere elongation. | 24879463 |
| 2015-04-04 10:15:00 | Autonomous localization of Est1p to the nucleus via the classical nuclear import pathway contributes to normal telomere length maintenance. | 24906415 |
| 2014-06-28 10:22:00 | Esl1 has no telomere-related functions, but contributes to the regulation of adaptive gene expression responses. | 23893744 |
| 2013-05-04 11:43:00 | It is possible that the intramolecular G-quadruplex promoting activity of Est1 is biologically relevant in telomere replication in vivo. | 23376615 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
EST1_YEAST
UniprotKB:
P17214
UniParc:
UPI0000036C74
EMBL:
U19027,
J04849,
BK006945
EnsemblGenome:
YLR233C
KO:
sce:YLR233C
|
| Nucleutide sequences |
EMBL-CDS:
DAA09549.1,
AAB67418.1,
AAA66908.1
Gene_ORFName:
L8083.15
EnsemblGenome_TRS:
YLR233C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR233C
RefSeq:
NP_013334.1
|
| Others |
UniRef100:
UniRef100_P17214
UniRef90:
UniRef90_P17214
UniRef50:
UniRef50_P17214
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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