| Type | Description |
|---|---|
| Definition | ubiquitin ligase complex subunit HRD3 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:20:00 | cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3: results suggest that Hrd1 forms a retro-translocation channel for the movement of misfolded polypeptides through the endoplasmic reticulum membrane | 28682307 |
| 2016-12-24 11:13:00 | direct component of Hrd3 is phenotypically as important as Hrd1 in the native HRD complex. Hrd3 was required the E3 activity of Hrd1, rather than substrate or E2 recruitment to Hrd1. Although Hrd1 can function in some circumstances independent of Hrd3, these studies show an indispensable role for Hrd3 in living cells. | 27170191 |
| 2015-10-03 10:31:00 | Data indicate that lysine arginine (KR) mutation causes moderate structural changes in Hrd3 protein. | 25428985 |
| 2011-08-06 11:13:00 | Data show that Der1p appears to have a role in a pathway that is parallel to that involving Hrd3p. | 21486563 |
| 2010-01-21 00:00:00 | Results suggest that Hrd3p recognises proteins that deviate from their native conformation. | 16845381 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HRD3_YEAST
UniprotKB:
Q05787
UniParc:
UPI0000069F78
EMBL:
U14913,
BK006945
EnsemblGenome:
YLR207W
KO:
sce:YLR207W
|
| Nucleutide sequences |
EMBL-CDS:
AAB67427.1,
DAA09524.1
EnsemblGenome_TRS:
YLR207W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR207W
RefSeq:
NP_013308.1
|
| Others |
UniRef100:
UniRef100_Q05787
UniRef90:
UniRef90_Q05787
UniRef50:
UniRef50_Q05787
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员